General Guidelines Chapter 2 of the ICD-10-CM contains the codes for most benign and all malignant neoplasms. Certain benign neoplasms, such as prostatic adenomas, may be found in the specific body system chapters. To properly code a neoplasm, it is necessary to determine from the record if the neoplasm is benign, in-situ, malignant, or of uncertain histologic behavior. If malignant, any secondary (metastatic) sites should also be determined. Primary malignant neoplasms overlapping site boundaries A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous such as tumors in different quadrants of the same breast, codes for each site should be assigned. Malignant neoplasm of ectopic tissue Malignant neoplasms of ectopic tissue are to be coded to the site of origin mentioned, e.g., ectopic pancreatic malignant neoplasms involving the stomach are coded to malignant neoplasm of pancreas, unspecified (C25.9). The neoplasm table in the Alphabetic Index should be referenced first. However, if the histological term is documented, that term should be referenced first, rather than going immediately to the Neoplasm Table, in order to determine which column in the Neoplasm Table is appropriate. For example, if the documentation indicates “adenoma,” refer to the term in the Alphabetic Index to review the entries under this term and the instructional note to “see also neoplasm, by site, benign.” The table provides the proper code based on the type of neoplasm and the site. It is important to select the proper column in the table that corresponds to the type of neoplasm. The Tabular List should then be referenced to verify that the correct code has been selected from the table and that a more specific site code does not exist. See Section I.C.21. Factors influencing health status and contact with health services, Status, for information regarding Z15.0, codes for genetic susceptibility to cancer.
D46.9
BookmarkMyelodysplastic syndrome, unspecified
Filed alongside this entry 777
under Syndrome
- 4H G11.5
- 5q minus NOS D46.C
- 22q13.3 deletion Q93.52
- 48,XXXX Q97.1
- 49,XXXXX Q97.1
- abnormal innervation H02.519
- abstinence, neonatal P96.1
- acid pulmonary aspiration, obstetric O74.0
- activated phosphoinositide 3-kinase delta syndrome [APDS] D81.82
- acute abdominal R10.0
- acute respiratory distress (adult) (child) J80
- Adair-Dighton Q78.0
- Adams-Stokes (-Morgagni) I45.9
- adiposogenital E23.6
- adrenogenital E25.9
- afferent loop NEC K91.89
- Aicardi-Goutières E79.81
- Alagille (-Watson) Q44.71
- Alder's D72.0
- Aldrich (-Wiskott) D82.0
- alien hand R41.4
- Alpha-gal Z91.014
- Alport Q87.81
- alveolar hypoventilation E66.2
- alveolocapillary block J84.10
- amyostatic (Wilson's disease) E83.01
- androgen insensitivity E34.50
- androgen resistance E34.50
- Angelman Q93.51
- ankyloglossia superior Q38.1
- antibody deficiency D80.9
- anticardiolipin (-antibody) D68.61
- antidepressant discontinuation T43.205
- antiphospholipid (-antibody) D68.61
- aortomesenteric duodenum occlusion K31.5
- apical ballooning (transient left ventricular) I51.81
- arcuate ligament I77.4
- argentaffin, argintaffinoma E34.09
- Arrillaga-Ayerza I27.0
- arterial tortuosity Q87.82
- arteriovenous steal T82.898
- Asherman's N85.6
- ataxia-telangiectasia G11.3
- auriculotemporal G50.8
- autoerythrocyte sensitization (Gardner-Diamond) D69.2
- autoimmune polyglandular E31.0
- autoimmune lymphoproliferative [ALPS] D89.82
- autoinflammatory M04.9
- Avellis' G46.8
- Axenfeld-Rieger Q13.81
- Ayerza (-Arrillaga) I27.0
- Babinski-Nageotte G83.89
- Bakwin-Krida Q78.5
- Bardet-Biedl Q87.83
- bare lymphocyte D81.6
- Barré-Guillain G61.0
- Barré-Liéou M53.0
- Barsony-Polgar K22.4
- Barsony-Teschendorf K22.4
- Barth E78.71
- Bartter's E26.81
- basal cell nevus Q87.89
- Basedow's E05.00
- basilar artery G45.0
- Batten-Steinert G71.11
- Beals Q87.40
- Beau's I51.5
- Beck's I65.8
- Benedikt's G46.3
- Béquez César (-Steinbrinck-Chédiak-Higashi) E70.330
- Berardinelli-Siep E88.12
- big spleen D73.1
- bilateral polycystic ovarian E28.2
- Birt-Hogg-Dube syndrome Q87.89
- Björck (-Thorsen) E34.09
- Blackfan-Diamond D61.01
- Blau M04.8
- blind loop K90.2
- blue sclera Q78.0
- blue toe I75.02
- Boder-Sedgewick G11.3
- Boerhaave's K22.3
- Borjeson Forssman Lehmann Q89.89
- Bouillaud's I01.9
- Bourneville (-Pringle) Q85.1
- Bouveret (-Hoffman) I47.9
- brachial plexus G54.0
- bradycardia-tachycardia I49.5
- brain (nonpsychotic) F09
- brain stem stroke G46.3
- Brandt's (acrodermatitis enteropathica) E83.2
- BRCA1-cancer predisposition QA1.790
- BRCA2-cancer predisposition QA1.791
- broad ligament laceration N83.8
- Brock's J98.11
- bronchiolitis obliterans J44.81
- bronze baby P83.88
- Brown-Sequard G83.81
- Brugada I49.81
- bubbly lung P27.0
- Buchem's M85.2
- Budd-Chiari I82.0
- bulbar (progressive) G12.22
- Bürger-Grütz E78.3
- Burke's K86.89
- Burnett's (milk-alkali) E83.52
- burning feet E53.9
- Bywaters' T79.5
- Call-Fleming I67.841
- cannabinoid hyperemesis R11.16
- cannabis hyperemesis R11.16
- carbohydrate-deficient glycoprotein (CDGS) E77.8
- carcinogenic thrombophlebitis I82.1
- carcinoid E34.00
- cardiac asthma I50.1
- cardiacos negros I27.0
- cardiofaciocutaneous Q87.89
- cardiopulmonary-obesity E66.2
- cardiorespiratory distress (idiopathic) , newborn P22.0
- carpal tunnel G56.0
- Cassidy (-Scholte) E34.09
- cat cry Q93.4
- cat eye Q92.8
- cauda equina G83.4
- celiac K90.0
- central pain G89.0
- cervical (root) M53.1
- cervicobrachial (diffuse) M53.1
- cervicocranial M53.0
- cervicodorsal outlet G54.2
- cervicothoracic outlet G54.0
- Céstan (-Raymond) I65.8
- Charcot's (angina cruris) (intermittent claudication) I73.9
- Charcot-Weiss-Baker G90.09
- CHARGE Q89.89
- Chédiak-Higashi (-Steinbrinck) E70.330
- chest wall R07.1
- Chiari's (hepatic vein thrombosis) I82.0
- Chilaiditi's Q43.3
- chondrocostal junction M94.0
- chondroectodermal dysplasia Q77.6
- chromosome 4 short arm deletion Q93.3
- chromosome 5 short arm deletion Q93.4
- Churg-Strauss M30.1
- Clarke-Hadfield K86.89
- Clerambault's automatism G93.89
- clinically isolated G37.9
- Clouston's (hidrotic ectodermal dysplasia) Q82.4
- clumsiness, clumsy child F82
- cluster headache G44.009
- Coffin-Lowry Q89.89
- cold injury (newborn) P80.0
- combined immunity deficiency D81.9
- compartment (deep) (posterior) (traumatic) T79.A0
- compression T79.5
- concussion F07.81
- congestion-fibrosis (pelvic) , female N94.89
- congestive dysmenorrhea N94.6
- Conn's E26.01
- connective tissue M35.9
- conus medullaris G95.81
- Costen's (complex) M26.69
- costochondral junction M94.0
- costoclavicular G54.0
- costovertebral E22.0
- craniovertebral M53.0
- cri-du-chat Q93.4
- crib death R99
- croup J05.0
- crush T79.5
- CTNNB1 Q87.88
- Curschmann (-Batten) (-Steinert) G71.11
- Cushing's E24.9
- cryopyrin-associated periodic M04.2
- cryptophthalmos Q87.0
- cystic duct stump K91.5
- cytokine release D89.839
- Dana-Putnam D51.0
- Danbolt (-Cross) (acrodermatitis enteropathica) E83.2
- Dandy-Walker Q03.1
- Danlos' Q79.60
- Degos' I77.89
- Déjérine-Roussy G89.0
- delayed sleep phase G47.21
- demyelinating G37.9
- depersonalization (-derealization) F48.1
- De Quervain E34.51
- de Toni-Fanconi (-Debré) E72.09
- de Vivo syndrome E74.810
- diabetes mellitus in newborn infant P70.2
- dialysis associated steal T82.898
- Diamond-Blackfan D61.01
- Diamond-Gardener D69.2
- DIC (diffuse or disseminated intravascular coagulopathy) D65
- di George's D82.1
- Dighton's Q78.0
- disequilibrium E87.8
- Döhle body-panmyelopathic D72.0
- dorsolateral medullary G46.4
- double athetosis G80.3
- Down Q90.9
- Dravet (intractable) G40.834
- Dresbach's (elliptocytosis) D58.1
- DRESS (drug rash with eosinophilia and systemic symptoms) D72.12
- Dressler's (postmyocardial infarction) I24.1
- drug rash with eosinophilia and systemic symptoms (DRESS) D72.12
- drug withdrawal, infant of dependent mother P96.1
- dry eye H04.12
- dumping (postgastrectomy) K91.1
- Dupré's (meningism) R29.1
- dysmetabolic X E88.810
- dyspraxia, developmental F82
- Eagle-Barrett Q79.4
- Ebstein's Q22.5
- ectopic ACTH E24.3
- eczema-thrombocytopenia D82.0
- Eddowes' Q78.0
- effort (psychogenic) F45.8
- Eisenmenger's I27.83
- Ehlers-Danlos Q79.60
- Ekman's Q78.0
- electric feet E53.8
- Ellis-van Creveld Q77.6
- empty nest Z60.0
- endocrine-hypertensive E27.0
- eosinophilia-myalgia M35.89
- Erdheim-Chester (ECD) E88.89
- Erdheim's E22.0
- erythrocyte fragmentation D59.4
- Evans D69.41
- exhaustion F48.8
- extrapyramidal G25.9
- eyelid-malar-mandible Q87.0
- Faber's D50.9
- facet M47.89
- facet joint M47.819
- facial pain, paroxysmal G50.0
- Fallot's Q21.3
- familial cold autoinflammatory M04.2
- familial eczema-thrombocytopenia (Wiskott-Aldrich) D82.0
- Fanconi (-de Toni) (-Debré) E72.09
- faulty bowel habit K59.39
- Feil-Klippel (brevicollis) Q76.1
- fertile eunuch E23.0
- Fiedler's I40.1
- first arch Q87.0
- fish odor E72.89
- Fisher's G61.0
- Fitz's K85.80
- Flajani (-Basedow) E05.00
- flush E34.09
- Foix-Alajouanine G95.19
- Fong's Q87.2
- food protein-induced enterocolitis (FPIES) K52.21
- foramen magnum G93.5
- Foster-Kennedy H47.14
- Foville's (peduncular) G46.3
- FOXG1 QA0.0151
- fragile X Q99.2
- Franceschetti Q75.4
- Friderichsen-Waterhouse A39.1
- Froin's G95.89
- frontal lobe F07.0
- Fukuhara E88.49
- Gaisböck's D75.1
- ganglion (basal ganglia brain) G25.9
- Gardner-Diamond D69.2
- gastrojejunal loop obstruction K91.89
- Gee-Herter-Heubner K90.0
- Gelineau's G47.419
- genito-anorectal A55
- Gerstmann-Sträussler-Scheinker (GSS) A81.82
- Gianotti-Crosti L44.4
- giant platelet (Bernard-Soulier) D69.19
- Gilles de la Tourette's F95.2
- Glass Q87.89
- Gleich's D72.118
- goiter-deafness E07.1
- Goldberg Q89.89
- Goldberg-Maxwell E34.51
- Good's D83.8
- Gopalan's (burning feet) E53.8
- Gorlin's Q87.89
- Gougerot-Blum L81.7
- Gouley's I31.1
- Gower's R55
- gray or grey (newborn) P93.0
- Gubler-Millard G46.3
- Guillain-Barré (-Strohl) G61.0
- Gulf war T75.830
- gustatory sweating G50.8
- Hadfield-Clarke K86.89
- Hamman's J98.19
- hand-foot L27.1
- hand-shoulder G90.89
- hantavirus (cardio)-pulmonary (HPS) (HCPS) B33.4
- Hao-Fountain (HAFOUS) Q87.87
- happy puppet Q93.51
- Harada's H30.81
- Hayem-Faber D50.9
- headache NEC G44.89
- Heberden's I20.89
- Hedinger's E34.01
- Hegglin's D72.0
- HELLP (hemolysis, elevated liver enzymes and low platelet count) O14.2
- hemolytic-uremic D59.30
- hemophagocytic, infection-associated D76.2
- Henoch-Schönlein D69.0
- hepatic flexure K59.89
- hepatopulmonary K76.81
- hepatorenal K76.7
- hepatourologic K76.7
- hereditary alpha tryptasemia D89.44
- Herter (-Gee) (nontropical sprue) K90.0
- Heubner-Herter K90.0
- Heyd's K76.7
- Hilger's G90.09
- histiocytic D76.3
- histiocytosis NEC D76.3
- HIV infection, acute B20
- Hoffmann-Werdnig G12.0
- Hollander-Simons E88.19
- Hoppe-Goldflam G70.00
- Horner's G90.2
- hungry bone E83.81
- hunterian glossitis D51.0
- Hunt's (herpetic geniculate ganglionitis) (neuralgia) B02.21
- Hutchinson's triad A50.53
- hyperabduction G54.0
- hyperammonemia-hyperornithinemia-homocitrullinemia E72.4
- hypereosinophilic (HES) D72.119
- hyperimmunoglobulin D M04.1
- hyperimmunoglobulin E (IgE) D82.4
- hyperkalemic E87.5
- hypermobility M35.7
- hypernatremia E87.0
- hyperosmolarity (see also, Diabetes, by type, with hyperosmolarity) E87.0
- hyperperfusion G97.82
- hypersplenic D73.1
- hypertransfusion, newborn P61.1
- hyperventilation F45.8
- hypoglycemic (familial) (neonatal) E16.2
- hypokalemic E87.6
- hyponatremic E87.1
- hypopituitarism E23.0
- hypoplastic left-heart Q23.4
- hypopotassemia E87.6
- hyposmolality E87.1
- hypotension, maternal O26.5
- hypothenar hammer I73.89
- hypoventilation, obesity (OHS) E66.2
- ICF (intravascular coagulation-fibrinolysis) D65
- iliotibial band M76.3
- immobility, immobilization (paraplegic) M62.3
- immune effector cell-associated neurotoxicity (ICANS) G92.00
- immune reconstitution D89.3
- immune reconstitution inflammatory [IRIS] D89.3
- immunity deficiency, combined D81.9
- impending coronary I20.0
- impingement, shoulder M75.4
- inappropriate secretion of antidiuretic hormone E22.2
- infantilism (pituitary) E23.0
- inferior vena cava I87.1
- inherited neoplasm predisposition syndrome of multiple systems, specified NEC QA1.798
- inspissated bile (newborn) P59.1
- institutional (childhood) F94.2
- insufficient sleep F51.12
- intermediate coronary (artery) I20.0
- intravascular coagulation-fibrinolysis (ICF) D65
- iodine-deficiency, congenital E00.9
- IRDS (idiopathic respiratory distress, newborn) P22.0
- IVC (intravascular coagulopathy) D65
- Ivemark's Q89.01
- Jackson's G83.89
- jaw-winking Q07.8
- Jervell-Lange-Nielsen I45.81
- jet lag G47.25
- Job's D71.8
- Joseph-Diamond-Blackfan D61.01
- jugular foramen G52.7
- Kabuki (type 1, due to KMT2D mutation) (type 2, due to KDM6A mutation) Q89.81
- Kanner's (autism) F84.0
- Kartagener's Q89.3
- Kelly's D50.1
- Kleefstra Q87.86
- Klein (e) -Levine G47.13
- Klippel-Feil (brevicollis) Q76.1
- König's K59.89
- Korsakoff (-Wernicke) (nonalcoholic) F04
- Kostmann's D70.0
- Krabbe's congenital muscle hypoplasia Q79.8
- lacunar NEC G46.7
- Lambert-Eaton G70.80
- Larsen's Q74.8
- Lassueur Graham-Little Piccardi L66.19
- Launois' E22.0
- Laurence-Moon Q87.84
- Lawrence E88.12
- Lemierre I80.8
- Lennox-Gastaut G40.812
- lenticular, progressive E83.01
- Leopold-Levi's E05.90
- Lev's I44.2
- Li-Fraumeni QA1.792
- Lichtheim's D51.0
- Lightwood's N25.89
- Lignac (de Toni) (-Fanconi) (-Debré) E72.09
- Likoff's I20.89
- limbic epilepsy personality F07.0
- liver-kidney K76.7
- lobotomy F07.0
- Loeys-Dietz Q87.A
- Löffler's J82.89
- long arm 18 or 21 deletion Q93.89
- long QT I45.81
- Louis-Barré G11.3
- lower radicular, newborn (birth injury) P14.8
- Luetscher's (dehydration) E86.0
- Lupus anticoagulant D68.62
- Lutembacher's Q21.19
- Lynch (due to EPCAM) (due to MLH1) (due to MSH2) (due to MSH6) (due to PMS2) QA1.71
- macrophage activation D76.1
- magnesium-deficiency R29.0
- Majeed M04.8
- Mal de Debarquement R42
- malabsorption K90.9
- Mallory-Weiss K22.6
- mandibulofacial dysostosis Q75.4
- maple-syrup-urine E71.0
- Marable's I77.4
- Marfan Q87.40
- Marie's (acromegaly) E22.0
- May (-Hegglin) D72.0
- McArdle (-Schmidt) (-Pearson) E74.04
- McQuarrie's E16.2
- meconium plug (newborn) P76.0
- MED13L (mediator complex subunit 13L) Q87.85
- median arcuate ligament I77.4
- mediator complex subunit 13L (MED13L) Q87.85
- Meekeren-Ehlers-Danlos Q79.6
- megavitamin-B6 E67.2
- Meige G24.4
- MELAS E88.41
- Mendelson's O74.0
- MERRF (myoclonic epilepsy associated with ragged-red fibers) E88.42
- metabolic E88.810
- metastatic carcinoid E34.00
- micrognathia-glossoptosis Q87.0
- midbrain NEC G93.89
- middle lobe (lung) J98.19
- middle radicular G54.0
- migraine G43.909
- Mikulicz' K11.8
- milk-alkali E83.52
- Millard-Gubler G46.3
- Miller-Dieker Q93.88
- Miller-Fisher G61.0
- Minkowski-Chauffard D58.0
- Mirizzi's K83.1
- MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy) E88.49
- monofixation H50.42
- Morel-Moore M85.2
- Morel-Morgagni M85.2
- Morgagni (-Morel) (-Stewart) M85.2
- Morgagni-Adams-Stokes I45.9
- Muckle-Wells M04.2
- mucocutaneous lymph node (acute febrile) (MCLS) M30.3
- multisystem inflammatory (in adults) (in children) M35.81
- Mounier-Kuhn Q32.4
- myasthenic G70.9
- myelodysplastic D46.9
- myeloid hypereosinophilic D72.118
- myelopathic pain G89.0
- myeloproliferative (chronic) D47.1
- myofascial pain M79.18
- Naffziger's G54.0
- nail patella Q87.2
- NARP (Neuropathy, Ataxia and Retinitis pigmentosa) E88.49
- neonatal abstinence P96.1
- nephrotic (congenital) N04.9
- neurologic neglect R41.4
- Nezelof's D81.4
- Niikawa-Kuroki Q89.81
- Nonne-Milroy-Meige Q82.0
- Nothnagel's vasomotor acroparesthesia I73.89
- obesity hypoventilation (OHS) E66.2
- oculomotor H51.9
- Ogilvie K59.81
- Oliver-McFarlane Q87.89
- oral allergy T78.19
- oral-facial-digital Q87.0
- Ormond's N13.5
- oro-facial-digital Q87.0
- os trigonum Q68.8
- Osler-Weber-Rendu I78.0
- osteoporosis-osteomalacia M83.8
- Osterreicher-Turner Q87.2
- oto-palatal-digital Q87.0
- outlet (thoracic) G54.0
- Owren's D68.2
- Paget-Schroetter I82.890
- paralytic G83.9
- Parinaud's H51.0
- paroxysmal facial pain G50.0
- Parry's E05.00
- Parsonage (-Aldren) -Turner G54.5
- patella clunk M25.86
- Paterson (-Brown) (-Kelly) D50.1
- pectoral girdle I77.89
- pectoralis minor I77.89
- pediatric acute-onset neuropsychiatric (PANS) D89.89
- pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) D89.89
- pediatric inflammatory multisystem M35.81
- Pelger-Huet D72.0
- pellagra-cerebellar ataxia-renal aminoaciduria E72.02
- pellagroid E52
- pelvic congestion-fibrosis, female N94.89
- penta X Q97.1
- perabduction I77.89
- periodic fever M04.1
- periodic fever, aphthous stomatitis, pharyngitis, and adenopathy [PFAPA] M04.8
- periurethral fibrosis N13.5
- Peutz-Jeghers Q85.89
- phantom limb (without pain) G54.7
- pharyngeal pouch D82.1
- Phelan-McDermid Q93.52
- Pickwickian E66.2
- PIE (pulmonary infiltration with eosinophilia) J82.89
- pigmentary pallidal degeneration (progressive) G23.0
- pineal E34.8
- pituitary E22.0
- plantar fascia M72.2
- plateau iris (post-iridectomy) (postprocedural) H21.82
- Plummer-Vinson D50.1
- pluricarential of infancy E40
- plurideficiency E40
- pluriglandular (compensatory) E31.8
- pneumatic hammer T75.21
- polyangiitis overlap M30.8
- polycarential of infancy E40
- polyglandular E31.8
- polysplenia Q89.09
- pontine NEC G93.89
- postbacterial fatigue G93.39
- postcardiotomy I97.0
- postcholecystectomy K91.5
- postcommissurotomy I97.0
- postconcussional F07.81
- postcontusional F07.81
- post-COVID (-19) U09.9
- postencephalitic F07.89
- post endometrial ablation N99.85
- post-polypectomy coagulation K91.89
- postgastrectomy (dumping) K91.1
- postgastric surgery K91.1
- postinfarction I24.1
- postinfectious fatigue G93.39
- postlaminectomy NEC M96.1
- postleukotomy F07.0
- postmastectomy lymphedema I97.2
- postmyocardial infarction I24.1
- postoperative NEC T81.9
- postpartum panhypopituitary (Sheehan) E23.0
- postpolio (myelitic) G14
- postthrombotic I87.009
- postvagotomy K91.1
- postvalvulotomy I97.0
- postviral NEC G93.31
- Potain's K31.0
- potassium intoxication E87.5
- Prader-Willi Q87.11
- Prader-Willi-like Q87.19
- precerebral artery (multiple) (bilateral) G45.2
- preinfarction I20.0
- preleukemic D46.9
- premature senility E34.8
- premenstrual dysphoric F32.81
- premenstrual tension N94.3
- Prinzmetal-Massumi R07.1
- prune belly Q79.4
- pseudoparalytica G70.00
- pseudo -Turner's Q87.19
- psycho-organic (nonpsychotic severity) F07.9
- PTEN (hamartoma) tumor Q85.81
- Putnam-Dana D51.0
- pyogenic arthritis, pyoderma gangrenosum, and acne [PAPA] M04.8
- pyramidopallidonigral G20.C
- QT interval prolongation I45.81
- rapid time-zone change G47.25
- Rasmussen G04.81
- Raymond (-Céstan) I65.8
- Raynaud's I73.00
- RDS (respiratory distress syndrome, newborn) P22.0
- reactive airways dysfunction J68.3
- Refsum's G60.1
- Reifenstein E34.52
- Rendu-Osler-Weber I78.0
- residual ovary N99.83
- resistant ovary E28.39
- restless legs G25.81
- restrictive allograft J4A.0
- retinoblastoma (familial) C69.2
- retroperitoneal fibrosis K68.2
- retroviral seroconversion (acute) Z21
- Reye's G93.7
- Ridley's I50.1
- Romano-Ward (prolonged QT interval) I45.81
- rotator cuff, shoulder M75.10
- rubella (congenital) P35.0
- Ruvalcaba-Myhre-Smith E71.440
- Rytand-Lipsitch I44.2
- salt-losing N28.89
- SATB2-associated Q87.89
- Scaglietti-Dagnini E22.0
- scalenus anticus (anterior) G54.0
- scapuloperoneal G71.09
- schizophrenic, of childhood NEC F20.9
- Schnitzler D47.2
- Scholte's E34.09
- Schroeder's E27.0
- Schüller-Christian C96.5
- Schwachman (-Diamond) D61.02
- Schwartz (-Jampel) G71.13
- Schwartz-Bartter E22.2
- scimitar Q26.8
- sclerocystic ovary E28.2
- Seitelberger's G31.89
- septicemic adrenal hemorrhage A39.1
- seroconversion, retroviral (acute) Z21
- serotonin G90.81
- serous meningitis G93.2
- severe acute respiratory (SARS) J12.81
- shaken infant T74.4
- shock (traumatic) T79.4
- shock-lung J80
- Shwachman (-Diamond) D61.02
- sick-euthyroid E07.81
- sideropenic D50.1
- Siemens' ectodermal dysplasia Q82.4
- Silfversköld's Q78.9
- Simons' E88.11
- sinus tarsi M25.57
- sinusitis-bronchiectasis-situs inversus Q89.3
- Sipple's E31.22
- sirenomelia Q87.2
- Sjögren M35.00
- Slocumb's E27.0
- slow flow, coronary I20.89
- Sluder's G44.89
- Smith-Magenis Q93.88
- Sneddon-Wilkinson L13.1
- Snyder-Robinson Q87.89
- Soto's Q87.3
- South African cardiomyopathy I42.89
- Spen's I45.9
- Spurway's Q78.0
- staphylococcal scalded skin L00
- Stein-Leventhal E28.2
- Stein's E28.2
- Stevens-Johnson syndrome L51.1
- Stewart-Morel M85.2
- Stickler Q89.89
- stiff baby Q89.89
- stiff man G25.82
- Stokes (-Adams) I45.9
- stone heart I50.1
- straight back, congenital Q76.49
- Sturge-Weber (-Dimitri) Q85.89
- subclavian steal G45.8
- subcoracoid-pectoralis minor G54.0
- subcostal nerve compression I77.89
- subphrenic interposition Q43.3
- suprarenal cortical E27.0
- supraspinatus M75.10
- Susac G93.49
- swallowed blood P78.2
- sweat retention L74.0
- Swyer Q99.1
- Symond's G93.2
- systemic inflammatory response (SIRS), of non-infectious origin (without organ dysfunction) R65.10
- tachycardia-bradycardia I49.5
- takotsubo I51.81
- TAR (thrombocytopenia with absent radius) Q87.2
- tarsal tunnel G57.5
- teething K00.7
- tegmental G93.89
- telangiectasic-pigmentation-cataract Q82.8
- temporomandibular joint-pain-dysfunction M26.62
- Terry's H44.2
- testicular feminization E34.51
- thalamic pain (hyperesthetic) G89.0
- thoracic outlet (compression) G54.0
- Thorson-Björck E34.09
- thrombocytopenia with absent radius (TAR) Q87.2
- thrombosis with thrombocytopenia D75.84
- thyroid-adrenocortical insufficiency E31.0
- Tietze's M94.0
- time-zone (rapid) G47.25
- Toni-Fanconi E72.09
- Touraine's Q79.8
- toxic shock A48.3
- transient left ventricular apical ballooning I51.81
- traumatic vasospastic T75.22
- Treacher Collins Q75.4
- triple X, female Q97.0
- trisomy Q92.9
- tropical wet feet T69.02
- Trousseau's I82.1
- tumor lysis (following antineoplastic chemotherapy) (spontaneous) NEC E88.3
- tumor necrosis factor receptor associated periodic (TRAPS) M04.1
- upward gaze H51.8
- uremia, chronic N18.9
- urethral N34.3
- urohepatic K76.7
- usher Q99.819
- vacuoles, E1 ubiquitin-activating enzyme, X-linked, autoinflammatory, somatic (VEXAS) M04.3
- vago-hypoglossal G52.7
- vanishing twin of one fetus or more O31.4
- vascular NEC in cerebrovascular disease G46.8
- vasoconstriction, reversible cerebrovascular I67.841
- vasomotor I73.9
- vasospastic (traumatic) T75.22
- vasovagal R55
- van Buchem's M85.2
- van der Hoeve's Q78.0
- VATER Q87.2
- velo-cardio-facial Q93.81
- vena cava (inferior) (superior) (obstruction) I87.1
- vertebro-basilar artery G45.0
- vertebrogenic (pain) M54.89
- VEXAS (vacuoles, E1 ubiquitin-activating enzyme, X-linked, autoinflammatory, somatic) M04.3
- Vinson-Plummer D50.1
- virus B34.9
- visceral larva migrans B83.0
- visual disorientation H53.8
- vitamin B6 deficiency E53.1
- vitreal corneal H59.01
- vitreous (touch) H59.01
- Vogt-Koyanagi H20.82
- Volkmann's T79.6
- von Hippel-Lindau Q85.83
- von Schroetter's I82.890
- Waldenström-Kjellberg D50.1
- Wallenberg's G46.3
- wasting (syndrome) due to underlying condition E88.A
- water retention E87.79
- Waterhouse (-Friderichsen) A39.1
- Weber-Gubler G46.3
- Weber-Leyden G46.3
- Weber's G46.3
- Wegener's M31.30
- Weingarten's (tropical eosinophilia) J82.89
- Weiss-Baker G90.09
- Werdnig-Hoffman G12.0
- Wermer's E31.21
- Werner's E34.8
- Wernicke-Korsakoff (nonalcoholic) F04
- Westphal-Strümpell E83.01
- whiplash S13.4
- whistling face Q87.0
- Wilkie's K55.1
- Wilkinson-Sneddon L13.1
- Williams Q93.82
- Wilson's (hepatolenticular degeneration) E83.01
- Wiskott-Aldrich D82.0
- Woakes' (ethmoiditis) J33.1
- Wright's (hyperabduction) G54.0
- X I20.9
- XXXX Q97.1
- XXXXX Q97.1
- XXXXY Q98.1
- XXY Q98.0
- Yao M04.8
- yellow nail L60.5
- Zahorsky's B08.5
- Zellweger syndrome E71.510
- Zellweger-like syndrome E71.541
Index entries, exactly as the book files them. This says they are listed together — not that any of them is documented in your chart.
How to use this page
Everything the published sources say about one code, on one page.
- Read the Excludes1 block first — it is the one that stops you coding this at all alongside another code.
- Excludes2, Code first, Use additional and Includes follow. A note inherited from a parent category is labelled with the category it came from, so you can see why it applies.
- Official Guidelines sit below. "Guidelines naming this code" cite the code or a range containing it; "Chapter guidance" is the general guidance for its chapter and is the weaker signal.
- Guideline text is quoted verbatim with its section number and page, so you can check it against the published document.
- Risk-model chips show which published CMS models map this code.
What this page does not do
- Guidance is quoted, never paraphrased — a paraphrase of a coding rule is a different rule.
- Medication candidates, where shown, are matched by condition *name* and are offered as candidates for you to judge. They are not "the drugs for this code".
Exclusions2never code together
Excludes1 — never code together. The excluded condition and this one are mutually exclusive.
Excludes2 — not included here, but the patient may have both. Code both when documented.
Instructional notes11
- Myelodysplasia NOS
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)T36-T50
- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).C25.9
Official Guidelines24names this code
ICD-10-CM Official Guidelines for Coding and Reporting, quoted in full. Published by CMS and NCHS; in the public domain.
If the malignancy is chiefly responsible for occasioning the patient admission/encounter and treatment is directed at the primary site, designate the primary malignancy as the principal/first-listed diagnosis. The only exception to this guideline is if the administration of chemotherapy, immunotherapy or external beam radiation therapy is chiefly responsible for occasioning the admission/encounter. In that case, assign the appropriate Z51.-- code as the first-listed or principal diagnosis, and the underlying diagnosis or problem for which the service is being performed as a secondary diagnosis.
When a patient is admitted because of a primary neoplasm with metastasis and treatment is directed toward the secondary site only, the secondary neoplasm is designated as the principal diagnosis even though the primary malignancy is still present.
Coding and sequencing of complications associated with the malignancies or with the therapy thereof are subject to the following guidelines:
When admission/encounter is for management of an anemia associated with the malignancy, and the treatment is only for anemia, the appropriate code for the malignancy is sequenced as the principal or first-listed diagnosis followed by the appropriate code for the anemia (such as code D63.0, Anemia in neoplastic disease).
When the admission/encounter is for management of an anemia associated with an adverse effect of the administration of chemotherapy or immunotherapy and the only treatment is for the anemia, the anemia code is sequenced first followed by the appropriate codes for the neoplasm and the adverse effect (T45.1X5-, Adverse effect of antineoplastic and immunosuppressive drugs). When the admission/encounter is for management of an anemia associated with an adverse effect of radiotherapy, the anemia code should be sequenced first, followed by the appropriate neoplasm code and code Y84.2, Radiological procedure and radiotherapy as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure.
When the admission/encounter is for management of dehydration due to the malignancy and only the dehydration is being treated (intravenous rehydration), the dehydration is sequenced first, followed by the code(s) for the malignancy.
procedure When the admission/encounter is for treatment of a complication resulting from a surgical procedure, designate the complication as the principal or first-listed diagnosis if treatment is directed at resolving the complication.
When a primary malignancy has been previously excised or eradicated from its site and there is no further treatment directed to that site and there is no evidence of any existing primary malignancy at that site, a code from category Z85, Personal history of malignant neoplasm, should be used to indicate the former site of the malignancy. Any mention of extension, invasion, or metastasis to another site is coded as a secondary malignant neoplasm to that site. The secondary site may be the principal or first-listed diagnosis with the Z85 code used as a secondary code. See section I.C.2.t. Secondary malignant neoplasm of lymphoid tissue.
When an episode of care involves the surgical removal of a neoplasm, primary or secondary site, followed by adjunct chemotherapy or radiation treatment during the same episode of care, the code for the neoplasm should be assigned as principal or first-listed diagnosis.
therapy If a patient admission/encounter is chiefly for the administration of chemotherapy, immunotherapy or external beam radiation therapy for the treatment of a neoplasm, assign code Z51.0, Encounter for antineoplastic radiation therapy, or Z51.11, Encounter for antineoplastic chemotherapy, or Z51.12, Encounter for antineoplastic immunotherapy as the first-listed or principal diagnosis. If the reason for the encounter is more than one type of antineoplastic therapy, code Z51.0 and codes from subcategory Z51.1 may be assigned together, in which case one of these codes would be reported as a secondary diagnosis. The malignancy for which the therapy is being administered should be assigned as a secondary diagnosis. If a patient admission/encounter is for the insertion or implantation of radioactive elements (e.g., brachytherapy) the appropriate code for the malignancy is sequenced as the principal or first-listed diagnosis. Code Z51.0 should not be assigned.
When a patient is admitted for the purpose of external beam radiotherapy, immunotherapy or chemotherapy and develops complications such as uncontrolled nausea and vomiting or dehydration, the principal or first-listed diagnosis is Z51.0, Encounter for antineoplastic radiation therapy, or Z51.11, Encounter for antineoplastic chemotherapy, or Z51.12, Encounter for antineoplastic immunotherapy followed by any codes for the complications. When a patient is admitted for the purpose of insertion or implantation of radioactive elements (e.g., brachytherapy) and develops complications such as uncontrolled nausea and vomiting or dehydration, the principal or first-listed diagnosis is the appropriate code for the malignancy followed by any codes for the complications.
When the reason for admission/encounter is to determine the extent of the malignancy, or for a procedure such as paracentesis or thoracentesis, the primary malignancy or appropriate metastatic site is designated as the principal or first-listed diagnosis, even though chemotherapy or radiotherapy is administered.
associated with neoplasms Symptoms, signs, and ill-defined conditions listed in Chapter 18 characteristic of, or associated with, an existing primary or secondary site malignancy cannot be used to replace the malignancy as principal or first-listed diagnosis, regardless of the number of admissions or encounters for treatment and care of the neoplasm. See section I.C.21. Factors influencing health status and contact with health services, Encounter for prophylactic organ removal.
See Section I.C.6. for information on coding admission/encounter for pain control/management.
A patient may have more than one malignant tumor in the same organ. These tumors may represent different primaries or metastatic disease, depending on the site. Should the documentation be unclear, the provider should be queried as to the status of each tumor so that the correct codes can be assigned.
Code C80.0, Disseminated malignant neoplasm, unspecified, is for use only in those cases where the patient has advanced metastatic disease and no known primary or secondary sites are specified. It should not be used in place of assigning codes for the primary site and all known secondary sites.
Code C80.1, Malignant (primary) neoplasm, unspecified, equates to Cancer, unspecified. This code should only be used when no determination can be made as to the primary site of a malignancy. This code should rarely be used in the inpatient setting.
If the reason for the encounter is for treatment of a primary malignancy, assign the malignancy as the principal/first-listed diagnosis. The primary site is to be sequenced first, followed by any metastatic sites.
When an encounter is for a primary malignancy with metastasis and treatment is directed toward the metastatic (secondary) site(s) only, the metastatic site(s) is designated as the principal/first-listed diagnosis. The primary malignancy is coded as an additional code.
When a pregnant patient has a malignant neoplasm, a code from subcategory O9A.1-, Malignant neoplasm complicating pregnancy, childbirth, and the puerperium, should be sequenced first, followed by the appropriate code from Chapter 2 to indicate the type of neoplasm.
When an encounter is for management of a complication associated with a neoplasm, such as dehydration, and the treatment is only for the complication, the complication is coded first, followed by the appropriate code(s) for the neoplasm. The exception to this guideline is anemia. When the admission/encounter is for management of an anemia associated with the malignancy, and the treatment is only for anemia, the appropriate code for the malignancy is sequenced as the principal or first-listed diagnosis followed by code D63.0, Anemia in neoplastic disease.
neoplasm When an encounter is for treatment of a complication resulting from a surgical procedure performed for the treatment of the neoplasm, designate the complication as the principal/first-listed diagnosis. See the guideline regarding the coding of a current malignancy versus personal history to determine if the code for the neoplasm should also be assigned.
When an encounter is for a pathological fracture due to a neoplasm, and the focus of treatment is the fracture, a code from subcategory M84.5, Pathological fracture in neoplastic disease, should be sequenced first, followed by the code for the neoplasm. If the focus of treatment is the neoplasm with an associated pathological fracture, the neoplasm code should be sequenced first, followed by a code from M84.5 for the pathological fracture.
Index entries leading here5
Alongside this code8same parent — D46
Additional references
Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.