Reserved for future guideline expansion
D80.1
BookmarkNonfamilial hypogammaglobulinemia
Filed alongside this entry 3
under Hypogammaglobulinemia
Index entries, exactly as the book files them. This says they are listed together — not that any of them is documented in your chart.
Billable FY2027 2026-10-01 → 2027-09-30
How to use this page
Everything the published sources say about one code, on one page.
- Read the Excludes1 block first — it is the one that stops you coding this at all alongside another code.
- Excludes2, Code first, Use additional and Includes follow. A note inherited from a parent category is labelled with the category it came from, so you can see why it applies.
- Official Guidelines sit below. "Guidelines naming this code" cite the code or a range containing it; "Chapter guidance" is the general guidance for its chapter and is the weaker signal.
- Guideline text is quoted verbatim with its section number and page, so you can check it against the published document.
- Risk-model chips show which published CMS models map this code.
What this page does not do
- Guidance is quoted, never paraphrased — a paraphrase of a coding rule is a different rule.
- Medication candidates, where shown, are matched by condition *name* and are offered as candidates for you to judge. They are not "the drugs for this code".
Exclusions12never code together
D80-D89block
D50-D89chapter
Excludes2
- autoimmune disease (systemic) NOS (M35.9)M35.9
- certain conditions originating in the perinatal period (P00-P96)P00-P96
- complications of pregnancy, childbirth and the puerperium (O00-O9A)O00-O9A
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)Q00-Q99
- endocrine, nutritional and metabolic diseases (E00-E88)E00-E88
- human immunodeficiency virus [HIV] disease (B20)B20
- injury, poisoning and certain other consequences of external causes (S00-T88)S00-T88
- neoplasms (C00-D49)C00-D49
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)R00-R94
Excludes1 — never code together. The excluded condition and this one are mutually exclusive.
Excludes2 — not included here, but the patient may have both. Code both when documented.
Instructional notes6
Official Guidelines1names this code
ICD-10-CM Official Guidelines for Coding and Reporting, quoted in full. Published by CMS and NCHS; in the public domain.
Index entries leading here7
- Absence (of) (organ or part) (complete or partial)
- gamma globulin in blood D80.1
- Agammaglobulinemia (acquired (secondary)) (nonfamilial) D80.1
- Syndrome — see also Disease
- Arthritis, arthritic (acute) (chronic) (nonpyogenic) (subacute) M19.90
- in (due to)
- hypogammaglobulinemia D80.1
- in (due to)
- Disease, diseased — see also Syndrome
- Deficiency, deficient
- gammaglobulin in blood D80.1
- Hypogammaglobulinemia D80.1
- nonfamilial D80.1
Alongside this code9same parent — D80
D80.0 Hereditary hypogammaglobulinemia D80.2 Selective deficiency of immunoglobulin A [IgA] D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses D80.4 Selective deficiency of immunoglobulin M [IgM] D80.5 Immunodeficiency with increased immunoglobulin M [IgM] D80.6 Antibody defic w near-norm immunoglob or w hyperimmunoglob D80.7 Transient hypogammaglobulinemia of infancy D80.8 Other immunodeficiencies with predominantly antibody defects D80.9 Immunodeficiency with predominantly antibody defects, unsp
Additional references
AHA Coding Clinic® Licence required
Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.