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D75.81

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Myelofibrosis

Filed alongside this entry 5

under Myelofibrosis

Index entries, exactly as the book files them. This says they are listed together — not that any of them is documented in your chart.

Billable FY2027 2026-10-01 → 2027-09-30
How to use this page

Everything the published sources say about one code, on one page.

  1. Read the Excludes1 block first — it is the one that stops you coding this at all alongside another code.
  2. Excludes2, Code first, Use additional and Includes follow. A note inherited from a parent category is labelled with the category it came from, so you can see why it applies.
  3. Official Guidelines sit below. "Guidelines naming this code" cite the code or a range containing it; "Chapter guidance" is the general guidance for its chapter and is the weaker signal.
  4. Guideline text is quoted verbatim with its section number and page, so you can check it against the published document.
  5. Risk-model chips show which published CMS models map this code.

What this page does not do

  • Guidance is quoted, never paraphrased — a paraphrase of a coding rule is a different rule.
  • Medication candidates, where shown, are matched by condition *name* and are offered as candidates for you to judge. They are not "the drugs for this code".

All page guides →

Exclusions22never code together
D75.81code
Excludes1
  • acute myelofibrosis (C94.4-)C94.4-
  • idiopathic myelofibrosis (D47.1)D47.1
  • leukoerythroblastic anemia (D61.82)D61.82
  • myelofibrosis with myeloid metaplasia (D47.4)D47.4
  • myelophthisic anemia (D61.82)D61.82
  • myelophthisis (D61.82)D61.82
  • primary myelofibrosis (D47.1)D47.1
D75code
Excludes2
  • acute lymphadenitis (L04.-)L04.-
  • chronic lymphadenitis (I88.1)I88.1
  • enlarged lymph nodes (R59.-)R59.-
  • hypergammaglobulinemia NOS (D89.2)D89.2
  • lymphadenitis NOS (I88.9)I88.9
  • mesenteric lymphadenitis (acute) (chronic) (I88.0)I88.0
D50-D89chapter
Excludes2
  • autoimmune disease (systemic) NOS (M35.9)M35.9
  • certain conditions originating in the perinatal period (P00-P96)P00-P96
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)O00-O9A
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)Q00-Q99
  • endocrine, nutritional and metabolic diseases (E00-E88)E00-E88
  • human immunodeficiency virus [HIV] disease (B20)B20
  • injury, poisoning and certain other consequences of external causes (S00-T88)S00-T88
  • neoplasms (C00-D49)C00-D49
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)R00-R94

Excludes1 — never code together. The excluded condition and this one are mutually exclusive.

Excludes2 — not included here, but the patient may have both. Code both when documented.

Instructional notes6
D75.81code
Inclusion terms
  • Myelofibrosis NOS
  • Secondary myelofibrosis NOS
Code first
  • the underlying disorder, such as:
  • malignant neoplasm of breast (C50.-)C50.-
Use additional code
  • code, if applicable, for associated therapy-related myelodysplastic syndrome (D46.-)D46.-
  • code for adverse effect, if applicable, to identify drug (T45.1X5)T45.1X5
Official Guidelines1names this code

ICD-10-CM Official Guidelines for Coding and Reporting, quoted in full. Published by CMS and NCHS; in the public domain.

I.C.3 Chapter 3: Disease of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) names this code p.39

Reserved for future guideline expansion

Index entries leading here3
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) D64.9
  • Osteosclerosis Q78.2
  • Myelofibrosis D75.81
Alongside this code4same parent — D75.8
Additional references
AHA Coding Clinic® Licence required

Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.

Risk adjustment

CMS22HCC46 CMS28HCC19 ESRD21HCC46 ESRD24HCC46 HHS08HHS_HCC067 RX08HCC16

Presence is a property of the code. Untick a model to hide it everywhere.

This code

Billable
yes
Code set
FY2027
Parent
D75.8
Block
D70-D77
Siblings
4

Present FY2018–FY2027.