Reserved for future guideline expansion
D58.2
BookmarkOther hemoglobinopathies
Filed alongside this entry 7
under Hemoglobin
- AS genotype D57.3
- Constant Spring D58.2
- E-beta thalassemia D56.5
- fetal, hereditary persistence (HPFH) D56.4
- H Constant Spring D56.0
- low NOS D64.9
- S (Hb S) , heterozygous D57.3
Index entries, exactly as the book files them. This says they are listed together — not that any of them is documented in your chart.
Billable FY2027 2026-10-01 → 2027-09-30
How to use this page
Everything the published sources say about one code, on one page.
- Read the Excludes1 block first — it is the one that stops you coding this at all alongside another code.
- Excludes2, Code first, Use additional and Includes follow. A note inherited from a parent category is labelled with the category it came from, so you can see why it applies.
- Official Guidelines sit below. "Guidelines naming this code" cite the code or a range containing it; "Chapter guidance" is the general guidance for its chapter and is the weaker signal.
- Guideline text is quoted verbatim with its section number and page, so you can check it against the published document.
- Risk-model chips show which published CMS models map this code.
What this page does not do
- Guidance is quoted, never paraphrased — a paraphrase of a coding rule is a different rule.
- Medication candidates, where shown, are matched by condition *name* and are offered as candidates for you to judge. They are not "the drugs for this code".
Exclusions17never code together
D58.2code
Excludes1
- familial polycythemia (D75.0)D75.0D75.0
- Hb-M disease (D74.0)D74.0D74.0
- hemoglobin E-beta thalassemia (D56.5)D56.5D56.5
- hereditary persistence of fetal hemoglobin [HPFH] (D56.4)D56.4D56.4
- high-altitude polycythemia (D75.1)D75.1D75.1
- methemoglobinemia (D74.-)D74.-D74.-
- other hemoglobinopathies with thalassemia (D56.8)D56.8D56.8
D50-D89chapter
Excludes2
- autoimmune disease (systemic) NOS (M35.9)M35.9
- certain conditions originating in the perinatal period (P00-P96)P00-P96
- complications of pregnancy, childbirth and the puerperium (O00-O9A)O00-O9A
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)Q00-Q99
- endocrine, nutritional and metabolic diseases (E00-E88)E00-E88
- human immunodeficiency virus [HIV] disease (B20)B20
- injury, poisoning and certain other consequences of external causes (S00-T88)S00-T88
- neoplasms (C00-D49)C00-D49
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)R00-R94
Excludes1 — never code together. The excluded condition and this one are mutually exclusive.
Excludes2 — not included here, but the patient may have both. Code both when documented.
Instructional notes7
D58.2code
Inclusion terms
- Abnormal hemoglobin NOS
- Congenital Heinz body anemia
- Hb-C disease
- Hb-D disease
- Hb-E disease
- Hemoglobinopathy NOS
- Unstable hemoglobin hemolytic disease
Official Guidelines1names this code
ICD-10-CM Official Guidelines for Coding and Reporting, quoted in full. Published by CMS and NCHS; in the public domain.
Index entries leading here10
- Abnormal, abnormality, abnormalities — see also Anomaly
- hemoglobin (disease) D58.2
- Disease, diseased — see also Syndrome
- Trait (s)
- hemoglobin
- abnormal NEC D58.2
- hemoglobin
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) D64.9
- Arthritis, arthritic (acute) (chronic) (nonpyogenic) (subacute) M19.90
- in (due to)
- hemoglobinopathy NEC D58.2
- in (due to)
- Arthropathy M12.9
- in (due to)
- hemoglobinopathy NEC D58.2
- in (due to)
- Osteonecrosis M87.9
- secondary NEC M87.30
- due to
- hemoglobinopathy NEC D58.2
- carpus D58.2
- clavicle D58.2
- ulna D58.2
- vertebra D58.2
- femur D58.2
- fibula D58.2
- finger D58.2
- humerus D58.2
- ilium D58.2
- ischium D58.2
- metacarpus D58.2
- metatarsus D58.2
- multiple sites D58.2
- neck D58.2
- radius D58.2
- rib D58.2
- scapula D58.2
- skull D58.2
- specified NEC D58.2
- tarsus D58.2
- tibia D58.2
- toe D58.2
- hemoglobinopathy NEC D58.2
- due to
- secondary NEC M87.30
- Hemoglobin — see also condition
- Constant Spring D58.2
- Heinz body anemia, congenital D58.2
- Hemoglobinopathy (mixed) D58.2
Alongside this code4same parent — D58
Medications1
MED-RT files conditions by MeSH, which carves the world differently from ICD-10. These are name matches on this code's description, offered as candidates — not as an assertion that they are this code.
Additional references
AHA Coding Clinic® Licence required
Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.