General Guidelines Chapter 2 of the ICD-10-CM contains the codes for most benign and all malignant neoplasms. Certain benign neoplasms, such as prostatic adenomas, may be found in the specific body system chapters. To properly code a neoplasm, it is necessary to determine from the record if the neoplasm is benign, in-situ, malignant, or of uncertain histologic behavior. If malignant, any secondary (metastatic) sites should also be determined. Primary malignant neoplasms overlapping site boundaries A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous such as tumors in different quadrants of the same breast, codes for each site should be assigned. Malignant neoplasm of ectopic tissue Malignant neoplasms of ectopic tissue are to be coded to the site of origin mentioned, e.g., ectopic pancreatic malignant neoplasms involving the stomach are coded to malignant neoplasm of pancreas, unspecified (C25.9). The neoplasm table in the Alphabetic Index should be referenced first. However, if the histological term is documented, that term should be referenced first, rather than going immediately to the Neoplasm Table, in order to determine which column in the Neoplasm Table is appropriate. For example, if the documentation indicates “adenoma,” refer to the term in the Alphabetic Index to review the entries under this term and the instructional note to “see also neoplasm, by site, benign.” The table provides the proper code based on the type of neoplasm and the site. It is important to select the proper column in the table that corresponds to the type of neoplasm. The Tabular List should then be referenced to verify that the correct code has been selected from the table and that a more specific site code does not exist. See Section I.C.21. Factors influencing health status and contact with health services, Status, for information regarding Z15.0, codes for genetic susceptibility to cancer.
C88.2
BookmarkHeavy chain disease
Filed alongside this entry 585
under Disease, diseased
- absorbent system I87.8
- acid-peptic K30
- Acosta's T70.29
- Adams-Stokes (-Morgagni) (syncope with heart block) I45.9
- Addison's anemia (pernicious) D51.0
- adenoids (and tonsils) J35.9
- adrenal (capsule) (cortex) (gland) (medullary) E27.9
- ainhum L94.6
- akamushi (scrub typhus) A75.3
- Albers-Schönberg (marble bones) Q78.2
- Alexander G31.86
- alimentary canal K63.9
- alligator-skin Q80.9
- alpha heavy chain C88.3
- alpine T70.29
- altitude T70.20
- alveoli, teeth K08.9
- Alzheimer's G30.9
- Andersen's (glycogenosis IV) E74.09
- Andes T70.29
- Andrews' (bacterid) L08.89
- angiospastic I73.9
- antiglomerular basement membrane (anti- GBM) antibody M31.0
- Antopol E74.05
- anus K62.9
- aorta (nonsyphilitic) I77.9
- aortic (heart) (valve) I35.9
- Apollo B30.3
- appendix K38.9
- aqueous (chamber) H21.9
- arterial I77.9
- arteriolar (generalized) (obliterative) I77.9
- artery I77.9
- arthropod-borne NOS (viral) A94
- atticoantral, chronic H66.20
- Australian X A83.4
- autoimmune (systemic) NOS M35.9
- autoinflammatory M04.9
- Ayerza's (pulmonary artery sclerosis with pulmonary hypertension) I27.0
- Babington's (familial hemorrhagic telangiectasia) I78.0
- bacterial A49.9
- Baelz's (cheilitis glandularis apostematosa) K13.0
- bagasse J67.1
- Bang's (brucella abortus) A23.1
- Bannister's T78.3
- Barraquer (-Simons') (progressive lipodystrophy) E88.11
- Bartholin's gland N75.9
- basal ganglia G25.9
- Bateman's B08.1
- Batten-Steinert G71.11
- Battey A31.0
- Beard's (neurasthenia) F48.8
- behavioral, organic F07.9
- Beigel's (white piedra) B36.2
- Bernard-Soulier (thrombopathy) D69.19
- Biermer's (pernicious anemia) D51.0
- bile duct (common) (hepatic) K83.9
- biliary (tract) K83.9
- bird fancier's J67.2
- black lung J60
- bladder N32.9
- bleeder's D66
- blood D75.9
- Blount M92.51
- Bodechtel-Guttmann (subacute sclerosing panencephalitis) A81.1
- bone-marrow D75.9
- Borna A83.9
- Bornholm (epidemic pleurodynia) B33.0
- Bouchard's (myopathic dilatation of the stomach) K31.0
- Bouillaud's (rheumatic heart disease) I01.9
- Bourneville (-Brissaud) (tuberous sclerosis) Q85.1
- Bouveret (-Hoffmann) (paroxysmal tachycardia) I47.9
- bowel K63.9
- brain G93.9
- breast N64.9
- Bretonneau's (diphtheritic malignant angina) A36.0
- Brill's (recrudescent typhus) A75.1
- Brill-Zinsser (recrudescent typhus) A75.1
- Brocq-Duhring (dermatitis herpetiformis) L13.0
- bronchopulmonary J98.4
- bronchus NEC J98.09
- bronze Addison's E27.1
- budgerigar fancier's J67.2
- bullous L13.9
- Buerger's (thromboangiitis obliterans) I73.1
- Bürger-Grütz (essential familial hyperlipemia) E78.3
- caisson T70.3
- Canavan E75.28
- capillaries I78.9
- Carapata A68.0
- carcinoid E34.00
- cardiopulmonary, chronic I27.9
- cardiovascular (atherosclerotic) I25.10
- Castellani's A69.8
- Castleman (unicentric) (multicentric) D47.Z2
- cat-scratch A28.1
- Cavare's (familial periodic paralysis) G72.3
- cecum K63.9
- celiac (adult) (infantile) (with steatorrhea) K90.0
- cellular tissue L98.9
- central core G71.29
- cerebrospinal G96.9
- cerebrovascular I67.9
- cervix (uteri) (noninflammatory) N88.9
- Chabert's A22.9
- Chédiak-Steinbrinck (-Higashi) (congenital gigantism of peroxidase granules) E70.330
- chest J98.9
- Chiari's (hepatic vein thrombosis) I82.0
- Chicago B40.9
- Chignon B36.8
- chigo, chigoe B88.1
- childhood granulomatous D71.8
- Chinese liver fluke B66.1
- chlamydial A74.9
- cholecystic K82.9
- choroid H31.9
- Christmas D67
- chronic bullous of childhood L12.2
- chylomicron retention E78.3
- ciliary body H21.9
- circulatory (system) NEC I99.8
- collagen NOS (nonvascular) (vascular) M35.9
- colon K63.9
- colonic inflammatory bowel, unclassified (IBDU) K52.3
- compressed air T70.3
- Concato's (pericardial polyserositis) A19.9
- conjunctiva H11.9
- connective tissue, systemic (diffuse) M35.9
- Conor and Bruch's (boutonneuse fever) A77.1
- Cori's (glycogenosis III) E74.03
- corkhandler's or corkworker's J67.3
- cornea H18.9
- corpus cavernosum N48.9
- COVID-19 U07.1
- coxsackie (virus) NEC B34.1
- cranial nerve NOS G52.9
- Crocq's (acrocyanosis) I73.89
- Curschmann G71.11
- cytomegalic inclusion (generalized) B25.9
- cytomegaloviral B25.9
- Daae (-Finsen) (epidemic pleurodynia) B33.0
- Danon E74.05
- Débove's (splenomegaly) R16.1
- Degos' I77.89
- demyelinating, demyelinizating (nervous system) G37.9
- dense deposit N05.6
- de Quervain's (tendon sheath) M65.4
- Devergie's (pityriasis rubra pilaris) L44.0
- Devic's G36.0
- diaphorase deficiency D74.0
- diaphragm J98.6
- diarrheal, infectious NEC A09
- digestive system K92.9
- Dubois (thymus) A50.59
- Duchenne-Griesinger G71.01
- ductless glands E34.9
- Duhring's (dermatitis herpetiformis) L13.0
- duodenum K31.9
- Dupré's (meningism) R29.1
- Dupuytren's (muscle contracture) M72.0
- Durand-Nicholas-Favre (climatic bubo) A55
- Duroziez's (congenital mitral stenosis) Q23.2
- Ebola (virus) A98.4
- Ebstein's heart Q22.5
- echovirus NEC B34.1
- Eddowes' (brittle bones and blue sclera) Q78.0
- edentulous (alveolar) ridge K06.9
- Edsall's T67.2
- Eichstedt's (pityriasis versicolor) B36.0
- Eisenmenger's (irreversible) I27.83
- Ellis-van Creveld (chondroectodermal dysplasia) Q77.6
- end stage renal (ESRD) N18.6
- endocrine glands or system NEC E34.9
- endomyocardial (eosinophilic) I42.3
- English (rickets) E55.0
- enteroviral, enterovirus NEC B34.1
- epidemic B99.9
- epididymis N50.9
- Erb (-Landouzy) G71.02
- Erdheim-Chester (ECD) E88.89
- esophagus K22.9
- Eulenburg's (congenital paramyotonia) G71.19
- extrapyramidal G25.9
- eye H57.9
- eyeball H44.9
- eyeworm of Africa B74.3
- facial nerve (seventh) G51.9
- Fahr (of brain) G23.8
- fallopian tube (noninflammatory) N83.9
- familial periodic paralysis G72.3
- Fanconi ('s) D61.03
- Favre-Durand-Nicolas (climatic bubo) A55
- Fede's K14.0
- female pelvic inflammatory N73.9
- Fernels' (aortic aneurysm) I71.9
- Fiedler's (leptospiral jaundice) A27.0
- fifth B08.3
- fish-skin Q80.9
- flax-dresser's J66.1
- foot and mouth B08.8
- foot process N04.9
- Forbes' (glycogenosis III) E74.03
- Fordyce-Fox (apocrine miliaria) L75.2
- Fordyce's (ectopic sebaceous glands) (mouth) Q38.6
- Forestier's (rhizomelic pseudopolyarthritis) M35.3
- Fournier (gangrene) N49.3
- fourth B08.8
- Fox (-Fordyce) (apocrine miliaria) L75.2
- Franklin C88.2
- Frei's (climatic bubo) A55
- fungus NEC B49
- Gaisböck's (polycythemia hypertonica) D75.1
- gallbladder K82.9
- gamma heavy chain C88.2
- Gamna's (siderotic splenomegaly) D73.2
- Gamstorp's (adynamia episodica hereditaria) G72.3
- Gandy-Nanta (siderotic splenomegaly) D73.2
- ganister J62.8
- gastroesophageal reflux (GERD) K21.9
- gastrointestinal (tract) K92.9
- Gee (-Herter) (-Heubner) (-Thaysen) (nontropical sprue) K90.0
- Gerhardt's (erythromelalgia) I73.81
- Gibert's (pityriasis rosea) L42
- Gierke's (glycogenosis I) E74.01
- Gilles de la Tourette's (motor-verbal tic) F95.2
- gingiva K06.9
- gland (lymph) I89.9
- Glanzmann's (hereditary hemorrhagic thrombasthenia) D69.11
- globe H44.9
- glycogen storage E74.00
- Goldstein's (familial hemorrhagic telangiectasia) I78.0
- gonococcal NOS A54.9
- graft-versus-host (GVH) D89.813
- grainhandler's J67.8
- granulomatous (childhood) (chronic) D71.8
- Grisel's M43.6
- Gruby's (tinea tonsurans) B35.0
- Guillain-Barré G61.0
- Guinon's (motor-verbal tic) F95.2
- gum K06.9
- gynecological N94.9
- H (Hartnup's) E72.02
- Hageman (congenital factor XII deficiency) D68.2
- hair (color) (shaft) L67.9
- Hamman's (spontaneous mediastinal emphysema) J98.2
- hand, foot and mouth B08.4
- Hantavirus, with pulmonary manifestations B33.4
- Harada's H30.81
- Hartnup (pellagra-cerebellar ataxia-renal aminoaciduria) E72.02
- Hart's (pellagra-cerebellar ataxia-renal aminoaciduria) E72.02
- Hashimoto's (struma lymphomatosa) E06.3
- heart (organic) I51.9
- Heartland A93.8
- heavy chain NEC C88.2
- hematopoietic organs D75.9
- hemolytic (newborn) P55.9
- hemorrhagic D69.9
- Henoch (-Schönlein) (purpura nervosa) D69.0
- hepatobiliary K83.9
- hepatolenticular E83.01
- herpesviral, disseminated B00.7
- Hers' (glycogenosis VI) E74.09
- Herter (-Gee) (-Heubner) (nontropical sprue) K90.0
- Heubner-Herter (nontropical sprue) K90.0
- high fetal gene or hemoglobin thalassemia D56.9
- hip (joint) M25.9
- His (-Werner) (trench fever) A79.0
- Hodgson's I71.20
- hookworm B76.9
- host-versus-graft D89.813
- human immunodeficiency virus (HIV) B20
- Huntington's G10
- Hunt's (herpetic geniculate ganglionitis) (neuralgia) B02.21
- hydroxyapatite deposition M11.00
- hypophysis E23.7
- Iceland G93.39
- I-cell E77.0
- IgG4-related D89.84
- immune D89.9
- immunoproliferative (malignant) C88.9
- inclusion B25.9
- infectious, infective B99.9
- intestine K63.9
- iris H21.9
- iron metabolism or storage E83.10
- island (scrub typhus) A75.3
- jaw M27.9
- jigger B88.1
- Jourdain's (acute gingivitis) K05.00
- Kaschin-Beck (endemic polyarthritis) M12.10
- Katayama B65.2
- Kedani (scrub typhus) A75.3
- Keshan E59
- kidney (functional) (pelvis) N28.9
- Kimura D21.9
- Kinnier Wilson's (hepatolenticular degeneration) E83.01
- Klippel-Feil (brevicollis) Q76.1
- Kok Q89.89
- Korsakoff's (nonalcoholic) F04
- Kostmann's (infantile genetic agranulocytosis) D70.0
- kuru A81.81
- Kyasanur Forest A98.2
- Lafora body G40.C09
- Lancereaux-Mathieu (leptospiral jaundice) A27.0
- Landry's G61.0
- Larrey-Weil (leptospiral jaundice) A27.0
- larynx J38.7
- Ledderhose M72.2
- legionnaires' A48.1
- Lenegre's I44.2
- lens H27.9
- Lev's (acquired complete heart block) I44.2
- Lewy body (dementia) G31.83
- Lichtheim's (subacute combined sclerosis with pernicious anemia) D51.0
- Lightwood's (renal tubular acidosis) N25.89
- Lignac's (cystinosis) E72.04
- lip K13.0
- lipid-storage E75.6
- Lipschütz's N76.6
- liver (chronic) (organic) K76.9
- Lobo's (keloid blastomycosis) B48.0
- Lobstein's (brittle bones and blue sclera) Q78.0
- Ludwig's (submaxillary cellulitis) K12.2
- lumbosacral region M53.87
- lung J98.4
- Lutembacher's (atrial septal defect with mitral stenosis) Q21.19
- Lyme A69.20
- lymphatic (gland) (system) (channel) (vessel) I89.9
- lymphoproliferative D47.9
- Magitot's M27.2
- Manson's B65.1
- maple bark J67.6
- maple-syrup-urine E71.0
- Marburg (virus) A98.3
- Marion's (bladder neck obstruction) N32.0
- Mathieu's (leptospiral jaundice) A27.0
- Maxcy's A75.2
- McArdle (-Schmid-Pearson) (glycogenosis V) E74.04
- mediastinum J98.59
- medullary center (idiopathic) (respiratory) G93.89
- Meige's (chronic hereditary edema) Q82.0
- mental F99
- mesenchymal M35.9
- mesenteric embolic K55.039
- metabolic, metabolism E88.9
- metal-polisher's J62.8
- metastatic C79.9
- Mikulicz' (dryness of mouth, absent or decreased lacrimation) K11.8
- Milroy's (chronic hereditary edema) Q82.0
- minicore G71.29
- Minor's G95.19
- Minot's (hemorrhagic disease, newborn) P53
- Mitchell's (erythromelalgia) I73.81
- mitral (valve) I05.9
- mixed connective tissue M35.1
- MOG antibody G37.81
- moldy hay J67.0
- Monge's T70.29
- Morgagni-Adams-Stokes (syncope with heart block) I45.9
- Morgagni's (syndrome) (hyperostosis frontalis interna) M85.2
- Morvan's G60.8
- motor neuron (bulbar) (mixed type) (spinal) G12.20
- moyamoya I67.5
- mu heavy chain disease C88.2
- multicore G71.29
- multiminicore G71.29
- mushroom workers' J67.5
- mycotic B49
- myelin oligodendrocyte glycoprotein antibody G37.81
- myelodysplastic C94.6
- myelodysplastic/myeloproliferative neoplasm, unclassifiable C94.6
- myeloproliferative D47.1
- myocardium, myocardial I51.5
- myoneural G70.9
- Naegeli's Q82.8
- nails L60.9
- Nairobi (sheep virus) A93.8
- nasal J34.9
- nemaline body G71.21
- nervous system G98.8
- neuromuscular system G70.9
- Newcastle B30.8
- Nicolas (-Durand)-Favre (climatic bubo) A55
- nipple N64.9
- Nishimoto (-Takeuchi) I67.5
- nonarthropod-borne NOS (viral) B34.9
- nonautoimmune hemolytic D59.4
- Nonne-Milroy-Meige (chronic hereditary edema) Q82.0
- nose J34.9
- nutritional E63.9
- oast-house-urine E72.19
- obliterative vascular I77.1
- Opitz's (congestive splenomegaly) D73.2
- Oriental liver fluke B66.1
- Oriental lung fluke B66.4
- Ormond's N13.5
- Oropouche virus A93.0
- Osler-Rendu (familial hemorrhagic telangiectasia) I78.0
- osteofibrocystic E21.0
- Otto's M24.7
- ovary (noninflammatory) N83.9
- p110d-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI] D81.82
- pancreas K86.9
- panvalvular I08.9
- parametrium (noninflammatory) N83.9
- parasitic B89
- parathyroid (gland) E21.5
- Parkinson's G20.A1
- parodontal K05.6
- Parrot's (syphilitic osteochondritis) A50.02
- Paxton's (white piedra) B36.2
- pelvis, pelvic K6A.8
- penis N48.9
- periapical tissues NOS K04.90
- periodontal K05.6
- peritoneum K66.9
- persistent mucosal (middle ear) H66.20
- pharynx J39.2
- photochromogenic (acid-fast bacilli) (pulmonary) A31.0
- Pick's G31.01
- pigeon fancier's J67.2
- pineal gland E34.8
- Pinkus' (lichen nitidus) L44.1
- pinworm B80
- Piry virus A93.8
- pituitary (gland) E23.7
- pituitary-snuff-taker's J67.8
- pleura (cavity) J94.9
- pneumatic drill (hammer) T75.21
- Pollitzer's (hidradenitis suppurativa) L73.2
- polyethylene T84.05
- Pompe's (glycogenosis II) E74.02
- Posadas-Wernicke B38.9
- prepuce N47.8
- Pringle's (tuberous sclerosis) Q85.1
- prion, central nervous system A81.9
- prostate N42.9
- protozoal B64
- pseudo-Hurler's E77.0
- psychiatric F99
- Puente's (simple glandular cheilitis) K13.0
- puerperal O90.89
- pulp (dental) NOS K04.90
- pulseless M31.4
- Putnam's (subacute combined sclerosis with pernicious anemia) D51.0
- Pyle (-Cohn) (metaphyseal dysplasia) Q78.5
- ragpicker's or ragsorter's A22.1
- rectum K62.9
- Refsum's (heredopathia atactica polyneuritiformis) G60.1
- renal (functional) (pelvis) N28.9
- Rendu-Osler-Weber (familial hemorrhagic telangiectasia) I78.0
- respiratory (tract) J98.9
- retina, retinal H35.9
- rickettsial NOS A79.9
- Riga (-Fede) (cachectic aphthae) K14.0
- Ritter's L00
- Rivalta's (cervicofacial actinomycosis) A42.2
- Robles' (onchocerciasis) B73.01
- rod body G71.21
- Roger's (congenital interventricular septal defect) Q21.0
- Rosenthal's (factor XI deficiency) D68.1
- Rossbach's (hyperchlorhydria) K31.89
- Ross River B33.1
- Runeberg's (progressive pernicious anemia) D51.0
- sacroiliac NEC M53.3
- salivary gland or duct K11.9
- sandworm B76.9
- Schönlein (-Henoch) (purpura rheumatica) D69.0
- Schwalbe-Ziehen-Oppenheim G24.1
- Schwartz-Jampel G71.13
- sclera H15.9
- scrofulous (tuberculous) A18.2
- scrotum N50.9
- sebaceous glands L73.9
- seminal vesicle N50.9
- serum NEC T80.69
- sexually transmitted A64
- Sézary C84.1
- shimamushi (scrub typhus) A75.3
- shipyard B30.0
- sickle-cell D57.1
- silo-filler's J68.8
- simian B B00.4
- Simons' (progressive lipodystrophy) E88.11
- sin nombre virus B33.4
- Sirkari's B55.0
- sixth B08.20
- skin L98.9
- slim (HIV) B20
- small vessel I73.9
- Sneddon-Wilkinson (subcorneal pustular dermatosis) L13.1
- South African creeping B88.09
- spinal (cord) G95.9
- spinocerebellar (hereditary) G11.9
- spleen D73.9
- Startle Q89.89
- Steinert's G71.11
- Sticker's (erythema infectiosum) B08.3
- Stokes-Adams (syncope with heart block) I45.9
- stomach K31.9
- stonemason's J62.8
- striatopallidal system NEC G25.89
- Stuart-Prower (congenital factor X deficiency) D68.2
- Stuart's (congenital factor X deficiency) D68.2
- supporting structures of teeth K08.9
- suprarenal (capsule) (gland) E27.9
- sweat glands L74.9
- Sweeley-Klionsky E75.21
- swimming-pool granuloma A31.1
- Sylvest's (epidemic pleurodynia) B33.0
- sympathetic nervous system G90.9
- systemic tissue mast cell D47.02
- tanapox (virus) B08.71
- Tangier E78.6
- Tarral-Besnier (pityriasis rubra pilaris) L44.0
- Tauri's E74.09
- terminal vessel I73.9
- testis N50.9
- Thaysen-Gee (nontropical sprue) K90.0
- Thomsen G71.12
- throat J39.2
- thymus (gland) E32.9
- thyroid (gland) E07.9
- Tietze's M94.0
- tongue K14.9
- tonsils, tonsillar (and adenoids) J35.9
- tooth, teeth K08.9
- Tourette's F95.2
- trachea NEC J39.8
- tricuspid I07.9
- triglyceride-storage E75.5
- tsutsugamushi A75.3
- tube (fallopian) (noninflammatory) N83.9
- tubo-ovarian (noninflammatory) N83.9
- tubulo-interstitial N15.9
- Uhl's Q24.8
- Underwood's (sclerema neonatorum) P83.0
- ureter N28.9
- urethra N36.9
- urinary (tract) N39.9
- uterus (noninflammatory) N85.9
- uveal tract (anterior) H21.9
- vagabond's B85.1
- vagina, vaginal (noninflammatory) N89.9
- valve, valvular I38
- van Creveld-von Gierke (glycogenosis I) E74.01
- vas deferens N50.9
- vascular I99.9
- vasomotor I73.9
- vasospastic I73.9
- vein I87.9
- venereal A64
- viral, virus B34.9
- vitreous H43.9
- vocal cord J38.3
- Volkmann's, acquired T79.6
- von Eulenburg's (congenital paramyotonia) G71.19
- von Gierke's (glycogenosis I) E74.01
- von Willebrand (-Jürgens) (angiohemophilia) D68.00
- Vrolik's (osteogenesis imperfecta) Q78.0
- vulva (noninflammatory) N90.9
- Wallgren's (obstruction of splenic vein with collateral circulation) I87.8
- Wassilieff's (leptospiral jaundice) A27.0
- wasting NEC E88.A
- Waterhouse-Friderichsen A39.1
- Wegner's (syphilitic osteochondritis) A50.02
- Weil's (leptospiral jaundice of lung) A27.0
- Weir Mitchell's (erythromelalgia) I73.81
- Werdnig-Hoffmann G12.0
- Wermer's E31.21
- Werner-His (trench fever) A79.0
- Werner-Schultz (neutropenic splenomegaly) D73.81
- Wernicke-Posadas B38.9
- whipworm B79
- white blood cells D72.9
- white matter R90.82
- white-spot, meaning lichen sclerosus et atrophicus L90.0
- Wilkie's K55.1
- Wilkinson-Sneddon (subcorneal pustular dermatosis) L13.1
- Wilson's (hepatolenticular degeneration) E83.01
- woolsorter's A22.1
- yaba monkey tumor B08.72
- yaba pox (virus) B08.72
- Zika virus A92.5
- zoonotic, bacterial A28.9
Index entries, exactly as the book files them. This says they are listed together — not that any of them is documented in your chart.
How to use this page
Everything the published sources say about one code, on one page.
- Read the Excludes1 block first — it is the one that stops you coding this at all alongside another code.
- Excludes2, Code first, Use additional and Includes follow. A note inherited from a parent category is labelled with the category it came from, so you can see why it applies.
- Official Guidelines sit below. "Guidelines naming this code" cite the code or a range containing it; "Chapter guidance" is the general guidance for its chapter and is the weaker signal.
- Guideline text is quoted verbatim with its section number and page, so you can check it against the published document.
- Risk-model chips show which published CMS models map this code.
What this page does not do
- Guidance is quoted, never paraphrased — a paraphrase of a coding rule is a different rule.
- Medication candidates, where shown, are matched by condition *name* and are offered as candidates for you to judge. They are not "the drugs for this code".
Exclusions2never code together
Instructional notes11
- Franklin disease
- Gamma heavy chain disease
- Mu heavy chain disease
- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).C25.9
Official Guidelines24names this code
ICD-10-CM Official Guidelines for Coding and Reporting, quoted in full. Published by CMS and NCHS; in the public domain.
If the malignancy is chiefly responsible for occasioning the patient admission/encounter and treatment is directed at the primary site, designate the primary malignancy as the principal/first-listed diagnosis. The only exception to this guideline is if the administration of chemotherapy, immunotherapy or external beam radiation therapy is chiefly responsible for occasioning the admission/encounter. In that case, assign the appropriate Z51.-- code as the first-listed or principal diagnosis, and the underlying diagnosis or problem for which the service is being performed as a secondary diagnosis.
When a patient is admitted because of a primary neoplasm with metastasis and treatment is directed toward the secondary site only, the secondary neoplasm is designated as the principal diagnosis even though the primary malignancy is still present.
Coding and sequencing of complications associated with the malignancies or with the therapy thereof are subject to the following guidelines:
When admission/encounter is for management of an anemia associated with the malignancy, and the treatment is only for anemia, the appropriate code for the malignancy is sequenced as the principal or first-listed diagnosis followed by the appropriate code for the anemia (such as code D63.0, Anemia in neoplastic disease).
When the admission/encounter is for management of an anemia associated with an adverse effect of the administration of chemotherapy or immunotherapy and the only treatment is for the anemia, the anemia code is sequenced first followed by the appropriate codes for the neoplasm and the adverse effect (T45.1X5-, Adverse effect of antineoplastic and immunosuppressive drugs). When the admission/encounter is for management of an anemia associated with an adverse effect of radiotherapy, the anemia code should be sequenced first, followed by the appropriate neoplasm code and code Y84.2, Radiological procedure and radiotherapy as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure.
When the admission/encounter is for management of dehydration due to the malignancy and only the dehydration is being treated (intravenous rehydration), the dehydration is sequenced first, followed by the code(s) for the malignancy.
procedure When the admission/encounter is for treatment of a complication resulting from a surgical procedure, designate the complication as the principal or first-listed diagnosis if treatment is directed at resolving the complication.
When a primary malignancy has been previously excised or eradicated from its site and there is no further treatment directed to that site and there is no evidence of any existing primary malignancy at that site, a code from category Z85, Personal history of malignant neoplasm, should be used to indicate the former site of the malignancy. Any mention of extension, invasion, or metastasis to another site is coded as a secondary malignant neoplasm to that site. The secondary site may be the principal or first-listed diagnosis with the Z85 code used as a secondary code. See section I.C.2.t. Secondary malignant neoplasm of lymphoid tissue.
When an episode of care involves the surgical removal of a neoplasm, primary or secondary site, followed by adjunct chemotherapy or radiation treatment during the same episode of care, the code for the neoplasm should be assigned as principal or first-listed diagnosis.
therapy If a patient admission/encounter is chiefly for the administration of chemotherapy, immunotherapy or external beam radiation therapy for the treatment of a neoplasm, assign code Z51.0, Encounter for antineoplastic radiation therapy, or Z51.11, Encounter for antineoplastic chemotherapy, or Z51.12, Encounter for antineoplastic immunotherapy as the first-listed or principal diagnosis. If the reason for the encounter is more than one type of antineoplastic therapy, code Z51.0 and codes from subcategory Z51.1 may be assigned together, in which case one of these codes would be reported as a secondary diagnosis. The malignancy for which the therapy is being administered should be assigned as a secondary diagnosis. If a patient admission/encounter is for the insertion or implantation of radioactive elements (e.g., brachytherapy) the appropriate code for the malignancy is sequenced as the principal or first-listed diagnosis. Code Z51.0 should not be assigned.
When a patient is admitted for the purpose of external beam radiotherapy, immunotherapy or chemotherapy and develops complications such as uncontrolled nausea and vomiting or dehydration, the principal or first-listed diagnosis is Z51.0, Encounter for antineoplastic radiation therapy, or Z51.11, Encounter for antineoplastic chemotherapy, or Z51.12, Encounter for antineoplastic immunotherapy followed by any codes for the complications. When a patient is admitted for the purpose of insertion or implantation of radioactive elements (e.g., brachytherapy) and develops complications such as uncontrolled nausea and vomiting or dehydration, the principal or first-listed diagnosis is the appropriate code for the malignancy followed by any codes for the complications.
When the reason for admission/encounter is to determine the extent of the malignancy, or for a procedure such as paracentesis or thoracentesis, the primary malignancy or appropriate metastatic site is designated as the principal or first-listed diagnosis, even though chemotherapy or radiotherapy is administered.
associated with neoplasms Symptoms, signs, and ill-defined conditions listed in Chapter 18 characteristic of, or associated with, an existing primary or secondary site malignancy cannot be used to replace the malignancy as principal or first-listed diagnosis, regardless of the number of admissions or encounters for treatment and care of the neoplasm. See section I.C.21. Factors influencing health status and contact with health services, Encounter for prophylactic organ removal.
See Section I.C.6. for information on coding admission/encounter for pain control/management.
A patient may have more than one malignant tumor in the same organ. These tumors may represent different primaries or metastatic disease, depending on the site. Should the documentation be unclear, the provider should be queried as to the status of each tumor so that the correct codes can be assigned.
Code C80.0, Disseminated malignant neoplasm, unspecified, is for use only in those cases where the patient has advanced metastatic disease and no known primary or secondary sites are specified. It should not be used in place of assigning codes for the primary site and all known secondary sites.
Code C80.1, Malignant (primary) neoplasm, unspecified, equates to Cancer, unspecified. This code should only be used when no determination can be made as to the primary site of a malignancy. This code should rarely be used in the inpatient setting.
If the reason for the encounter is for treatment of a primary malignancy, assign the malignancy as the principal/first-listed diagnosis. The primary site is to be sequenced first, followed by any metastatic sites.
When an encounter is for a primary malignancy with metastasis and treatment is directed toward the metastatic (secondary) site(s) only, the metastatic site(s) is designated as the principal/first-listed diagnosis. The primary malignancy is coded as an additional code.
When a pregnant patient has a malignant neoplasm, a code from subcategory O9A.1-, Malignant neoplasm complicating pregnancy, childbirth, and the puerperium, should be sequenced first, followed by the appropriate code from Chapter 2 to indicate the type of neoplasm.
When an encounter is for management of a complication associated with a neoplasm, such as dehydration, and the treatment is only for the complication, the complication is coded first, followed by the appropriate code(s) for the neoplasm. The exception to this guideline is anemia. When the admission/encounter is for management of an anemia associated with the malignancy, and the treatment is only for anemia, the appropriate code for the malignancy is sequenced as the principal or first-listed diagnosis followed by code D63.0, Anemia in neoplastic disease.
neoplasm When an encounter is for treatment of a complication resulting from a surgical procedure performed for the treatment of the neoplasm, designate the complication as the principal/first-listed diagnosis. See the guideline regarding the coding of a current malignancy versus personal history to determine if the code for the neoplasm should also be assigned.
When an encounter is for a pathological fracture due to a neoplasm, and the focus of treatment is the fracture, a code from subcategory M84.5, Pathological fracture in neoplastic disease, should be sequenced first, followed by the code for the neoplasm. If the focus of treatment is the neoplasm with an associated pathological fracture, the neoplasm code should be sequenced first, followed by a code from M84.5 for the pathological fracture.
Index entries leading here2
Alongside this code5same parent — C88
Subordinate codes2
Additional references
Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.