E22.1

Hyperprolactinemia

Billable FY2026 2025-10-01 → 2026-09-30

Exclusions 8 never code together

E22code

Excludes1

Cushing's syndrome (E24.-)E24.-
Nelson's syndrome (E24.1)E24.1
overproduction of ACTH not associated with Cushing's disease (E27.0)E27.0
overproduction of pituitary ACTH (E24.0)E24.0
overproduction of thyroid-stimulating hormone (E05.8-)E05.8-

E20-E35block

Excludes1

galactorrhea (N64.3)N64.3
gynecomastia (N62)N62

E00-E89chapter

Excludes1

transitory endocrine and metabolic disorders specific to newborn (P70-P74)P70-P74

Excludes1 — never code together. The excluded condition and this one are mutually exclusive.

Instructional notes 2

E22.1code

Use additional code

code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)T36-T50 T36-T50

E00-E89chapter

Notes

All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.E05.8 E07.0 E16-E31 E34.-

Index entries leading here 1

Hyperprolactinemia E22.1

Alongside this code 4 same parent — E22

E22.0 Acromegaly and pituitary gigantism E22.2 Syndrome of inappropriate secretion of antidiuretic hormone E22.8 Other hyperfunction of pituitary gland E22.9 Hyperfunction of pituitary gland, unspecified

Medications 1

3 Hyperprolactinemia drugs

MED-RT files conditions by MeSH, which carves the world differently from ICD-10. These are name matches on this code's description, offered as candidates — not as an assertion that they are this code.

Additional references

AHA Coding Clinic® Licence required

Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.

Risk adjustment

CMS22HCC23 ESRD21HCC23 ESRD24HCC23 RX08HCC43

Presence is a property of the code. Untick a model to hide it everywhere.

This code

Billable: yes
Code set: FY2026
Parent: E22
Block: E20-E35
Siblings: 4

Present FY2024–FY2027.