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E22.0

Acromegaly and pituitary gigantism

Billable FY2026 2025-10-01 → 2026-09-30
Exclusions 11 never code together
E22.0code
Excludes1
  • constitutional gigantism (E34.4)E34.4E34.4
  • constitutional tall stature (E34.4)E34.4E34.4
  • increased secretion from endocrine pancreas of growth hormone-releasing hormone (E16.8)E16.8E16.8
E22code
Excludes1
  • Cushing's syndrome (E24.-)E24.-
  • Nelson's syndrome (E24.1)E24.1
  • overproduction of ACTH not associated with Cushing's disease (E27.0)E27.0
  • overproduction of pituitary ACTH (E24.0)E24.0
  • overproduction of thyroid-stimulating hormone (E05.8-)E05.8-
E20-E35block
Excludes1
  • galactorrhea (N64.3)N64.3
  • gynecomastia (N62)N62
E00-E89chapter
Excludes1
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)P70-P74

Excludes1 — never code together. The excluded condition and this one are mutually exclusive.

Instructional notes 2
E22.0code
Inclusion terms
  • Overproduction of growth hormone
E00-E89chapter
Notes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.E05.8E07.0E16-E31E34.-
Index entries leading here 13
  • Arthritis, arthritic (acute) (chronic) (nonpyogenic) (subacute) M19.90
    • due to or associated with
    • in (due to)
  • Arthropathy M12.9
    • in (due to)
  • Acromegaly, acromegalia E22.0
  • Syndrome — see also Disease
  • Marie's
    • disease or syndrome (acromegaly) E22.0
  • Erdheim's syndrome (acromegalic macrospondylitis) E22.0
  • Hypophyseal, hypophysis — see also condition
  • Gigantism (cerebral) (hypophyseal) (pituitary) E22.0
  • Hypersecretion
    • hormone (s)
  • Overproduction — see also Hypersecretion
  • Launois' syndrome (pituitary gigantism) E22.0
  • Macrospondylitis , acromegalic E22.0
  • Scaglietti-Dagnini syndrome E22.0
Alongside this code 4 same parent — E22
E22.1 Hyperprolactinemia E22.2 Syndrome of inappropriate secretion of antidiuretic hormone E22.8 Other hyperfunction of pituitary gland E22.9 Hyperfunction of pituitary gland, unspecified
Additional references
AHA Coding Clinic® Licence required

Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.

Risk adjustment

CMS22HCC23 CMS28HCC51 ESRD21HCC23 ESRD24HCC23 RX08HCC42

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This code

Billable
yes
Code set
FY2026
Parent
E22
Block
E20-E35
Siblings
4

Present FY2024–FY2027.