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D76.2

Hemophagocytic syndrome, infection-associated

Billable FY2026 2025-10-01 → 2026-09-30
Exclusions 24 never code together
D76code
Excludes1
  • (Abt-) Letterer-Siwe disease (C96.0)C96.0
  • eosinophilic granuloma (C96.6)C96.6
  • Hand-Schüller-Christian disease (C96.5)C96.5
  • histiocytic medullary reticulosis (C96.9)C96.9
  • histiocytic sarcoma (C96.A)C96.A
  • histiocytosis X, multifocal (C96.5)C96.5
  • histiocytosis X, unifocal (C96.6)C96.6
  • Langerhans-cell histiocytosis, multifocal (C96.5)C96.5
  • Langerhans-cell histiocytosis NOS (C96.6)C96.6
  • Langerhans-cell histiocytosis, unifocal (C96.6)C96.6
  • leukemic reticuloendotheliosis (C91.4-)C91.4-
  • lipomelanotic reticulosis (I89.8)I89.8
  • malignant histiocytosis (C96.A)C96.A
  • malignant reticulosis (C86.0)C86.0
  • nonlipid reticuloendotheliosis (C96.0)C96.0
D50-D89chapter
Excludes2
  • autoimmune disease (systemic) NOS (M35.9)M35.9
  • certain conditions originating in the perinatal period (P00-P96)P00-P96
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)O00-O9A
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)Q00-Q99
  • endocrine, nutritional and metabolic diseases (E00-E88)E00-E88
  • human immunodeficiency virus [HIV] disease (B20)B20
  • injury, poisoning and certain other consequences of external causes (S00-T88)S00-T88
  • neoplasms (C00-D49)C00-D49
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)R00-R94

Excludes1 — never code together. The excluded condition and this one are mutually exclusive.

Excludes2 — not included here, but the patient may have both. Code both when documented.

Instructional notes 1
D76.2code
Use additional code
  • code to identify infectious agent or disease.
Index entries leading here 1
  • Syndrome — see also Disease
    • macrophage activation D76.1
    • hemophagocytic, infection-associated D76.2
Alongside this code 2 same parent — D76
Additional references
AHA Coding Clinic® Licence required

Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.

Risk adjustment

CMS22HCC47 ESRD21HCC47 ESRD24HCC47

Presence is a property of the code. Untick a model to hide it everywhere.

This code

Billable
yes
Code set
FY2026
Parent
D76
Block
D70-D77
Siblings
2

Present FY2024–FY2027.