C96.0
Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis
Billable FY2026 2025-10-01 → 2026-09-30
Exclusions 4 never code together
Instructional notes 10
C96.0code
Inclusion terms
- Histiocytosis X, multisystemic
- Letterer-Siwe disease
C00-D49chapter
Notes
- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).C25.9
Index entries leading here 4
Alongside this code 7 same parent — C96
C96.2 Malignant mast cell neoplasm category C96.4 Sarcoma of dendritic cells (accessory cells) C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis C96.6 Unifocal Langerhans-cell histiocytosis C96.A Histiocytic sarcoma C96.Z Oth malig neoplm of lymphoid, hematpoetc and related tissue C96.9 Malig neoplm of lymphoid, hematpoetc and rel tissue, unsp
Additional references
AHA Coding Clinic® Licence required
Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.