I27.21
Secondary pulmonary arterial hypertension
Billable FY2026 2025-10-01 → 2026-09-30
Exclusions 11 never code together
I00-I99chapter
Excludes2
- certain conditions originating in the perinatal period (P04-P96)P04-P96
- certain infectious and parasitic diseases (A00-B99)A00-B99
- complications of pregnancy, childbirth and the puerperium (O00-O9A)O00-O9A
- congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)Q00-Q99
- endocrine, nutritional and metabolic diseases (E00-E88)E00-E88
- injury, poisoning and certain other consequences of external causes (S00-T88)S00-T88
- neoplasms (C00-D49)C00-D49
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)R00-R94
- systemic connective tissue disorders (M30-M36)M30-M36
- transient cerebral ischemic attacks and related syndromes (G45.-)G45.-
Excludes1 — never code together. The excluded condition and this one are mutually exclusive.
Excludes2 — not included here, but the patient may have both. Code both when documented.
Instructional notes 13
I27.21code
Inclusion terms
- (Associated) (drug-induced) (toxin-induced) pulmonary arterial hypertension NOS
- (Associated) (drug-induced) (toxin-induced) (secondary) group 1 pulmonary hypertension
Code also
- associated conditions if applicable, or adverse effects of drugs or toxins, such as:
- adverse effect of appetite depressants (T50.5X5)T50.5X5
- congenital heart disease (Q20-Q28)Q20-Q28
- human immunodeficiency virus [HIV] disease (B20)B20
- polymyositis (M33.2-)M33.2-
- portal hypertension (K76.6)K76.6
- rheumatoid arthritis (M05.-)M05.-
- schistosomiasis (B65.-)B65.-
- Sjögren syndrome (M35.0-)M35.0-
- systemic sclerosis (M34.-)M34.-
I27.2code
Code also
- associated underlying condition
Index entries leading here 1
Alongside this code 5 same parent — I27.2
Medications 2
MED-RT files conditions by MeSH, which carves the world differently from ICD-10. These are name matches on this code's description, offered as candidates — not as an assertion that they are this code.
Additional references
AHA Coding Clinic® Licence required
Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.