E88.3

Tumor lysis syndrome

Billable FY2026 2025-10-01 → 2026-09-30

Exclusions 8 never code together

E88code

Excludes1

histiocytosis X (chronic) (C96.6)C96.6

E70-E88block

Excludes1

androgen insensitivity syndrome (E34.5-)E34.5-
congenital adrenal hyperplasia (E25.0)E25.0
hemolytic anemias attributable to enzyme disorders (D55.-)D55.-
Marfan syndrome (Q87.4-)Q87.4-
5-alpha-reductase deficiency (E29.1)E29.1

Excludes2

Ehlers-Danlos syndromes (Q79.6-)Q79.6-

E00-E89chapter

Excludes1

transitory endocrine and metabolic disorders specific to newborn (P70-P74)P70-P74

Excludes1 — never code together. The excluded condition and this one are mutually exclusive.

Excludes2 — not included here, but the patient may have both. Code both when documented.

Instructional notes 5

E88.3code

Inclusion terms

Tumor lysis syndrome (spontaneous)
Tumor lysis syndrome following antineoplastic drug chemotherapy

Use additional code

code for adverse effect, if applicable, to identify drug (T45.1X5)T45.1X5 T45.1X5

E88code

Use additional code

codes for associated conditions

E00-E89chapter

Notes

All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.E05.8 E07.0 E16-E31 E34.-

Index entries leading here 2

Syndrome — see also Disease
- tumor lysis (following antineoplastic chemotherapy) (spontaneous) NEC E88.3
Tumor lysis syndrome (following antineoplastic chemotherapy) (spontaneous) NEC E88.3

Alongside this code 7 same parent — E88

E88.0 Disorders of plasma-protein metabolism, NEC category E88.1 Lipodystrophy, not elsewhere classified category E88.2 Lipomatosis, not elsewhere classified E88.4 Mitochondrial metabolism disorders category E88.8 Other specified metabolic disorders category E88.9 Metabolic disorder, unspecified E88.A Wasting disease (syndrome) due to underlying condition

Medications 1

3 Tumor Lysis Syndrome drugs

MED-RT files conditions by MeSH, which carves the world differently from ICD-10. These are name matches on this code's description, offered as candidates — not as an assertion that they are this code.

Additional references

AHA Coding Clinic® Licence required

Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.

Risk adjustment

Maps to no condition category in any loaded model.

Presence is a property of the code. Untick a model to hide it everywhere.

This code

Billable: yes
Code set: FY2026
Parent: E88
Block: E70-E88
Siblings: 7

Present FY2024–FY2027.