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E78.2

Mixed hyperlipidemia

Billable FY2026 2025-10-01 → 2026-09-30
Exclusions 10 never code together
E78code
Excludes1
E78.2code
Excludes1
  • cerebrotendinous cholesterosis [van Bogaert-Scherer- Epstein] (E75.5)E75.5E75.5
  • familial combined hyperlipidemia (E78.49)E78.49E78.49
E70-E88block
Excludes1
  • androgen insensitivity syndrome (E34.5-)E34.5-
  • congenital adrenal hyperplasia (E25.0)E25.0
  • hemolytic anemias attributable to enzyme disorders (D55.-)D55.-
  • Marfan syndrome (Q87.4-)Q87.4-
  • 5-alpha-reductase deficiency (E29.1)E29.1
Excludes2
  • Ehlers-Danlos syndromes (Q79.6-)Q79.6-
E00-E89chapter
Excludes1
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)P70-P74

Excludes1 — never code together. The excluded condition and this one are mutually exclusive.

Excludes2 — not included here, but the patient may have both. Code both when documented.

Instructional notes 10
E78.2code
Inclusion terms
  • Broad- or floating-betalipoproteinemia
  • Combined hyperlipidemia NOS
  • Elevated cholesterol with elevated triglycerides NEC
  • Fredrickson's hyperlipoproteinemia, type IIb or III
  • Hyperbetalipoproteinemia with prebetalipoproteinemia
  • Hypercholesteremia with endogenous hyperglyceridemia
  • Hyperlipidemia, group C
  • Tubo-eruptive xanthoma
  • Xanthoma tuberosum
E00-E89chapter
Notes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.E05.8E07.0E16-E31E34.-
Index entries leading here 18
  • Disease, diseased — see also Syndrome
  • Broad — see also condition
  • Betalipoproteinemia, broad or floating E78.2
  • Lipoproteinemia E78.5
  • Broad- or floating-betalipoproteinemia E78.2
  • Hyperlipemia, hyperlipidemia E78.5
  • High
  • Elevated, elevation
  • Findings, abnormal, inconclusive, without diagnosis — see also Abnormal
  • Cholesterol
    • elevated (high) E78.00
      • with elevated (high) triglycerides E78.2
  • Cirrhosis, cirrhotic (hepatic) (liver) K74.60
    • xanthomatous (biliary) K74.5
      • due to xanthomatosis (familial) (metabolic) (primary) E78.2
    • due to
  • Xanthoma (s), xanthomatosis (primary) (familial) (hereditary) E78.2
  • Dysbetalipoproteinemia (familial) E78.2
  • Frederickson's hyperlipoproteinemia, type
  • Hyperlipoproteinemia E78.5
  • Hyperbetalipoproteinemia (familial) E78.00
    • with prebetalipoproteinemia E78.2
  • Hypercholesterolemia (essential) (primary) (pure) E78.00
    • with hyperglyceridemia, endogenous E78.2
  • Xanthelasmatosis (essential) E78.2
Alongside this code 9 same parent — E78
E78.0 Pure hypercholesterolemia category E78.1 Pure hyperglyceridemia E78.3 Hyperchylomicronemia E78.4 Other hyperlipidemia category E78.5 Hyperlipidemia, unspecified E78.6 Lipoprotein deficiency E78.7 Disorders of bile acid and cholesterol metabolism category E78.8 Other disorders of lipoprotein metabolism category E78.9 Disorder of lipoprotein metabolism, unspecified
Additional references
AHA Coding Clinic® Licence required

Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.

Risk adjustment

RX08HCC47

Presence is a property of the code. Untick a model to hide it everywhere.

This code

Billable
yes
Code set
FY2026
Parent
E78
Block
E70-E88
Siblings
9

Present FY2024–FY2027.