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E10.21

Type 1 diabetes mellitus with diabetic nephropathy

Billable FY2026 2025-10-01 → 2026-09-30
Exclusions 10 never code together
E10code
Excludes1
  • diabetes mellitus due to underlying condition (E08.-)E08.-
  • drug or chemical induced diabetes mellitus (E09.-)E09.-
  • gestational diabetes (O24.4-)O24.4-
  • hyperglycemia NOS (R73.9)R73.9
  • neonatal diabetes mellitus (P70.2)P70.2
  • postpancreatectomy diabetes mellitus (E13.-)E13.-
  • postprocedural diabetes mellitus (E13.-)E13.-
  • secondary diabetes mellitus NEC (E13.-)E13.-
  • type 2 diabetes mellitus (E11.-)E11.-
E00-E89chapter
Excludes1
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)P70-P74

Excludes1 — never code together. The excluded condition and this one are mutually exclusive.

Instructional notes 10
E10code
Includes
  • brittle diabetes (mellitus)
  • diabetes (mellitus) due to autoimmune process
  • diabetes (mellitus) due to immune mediated pancreatic islet beta-cell destruction
  • idiopathic diabetes (mellitus)
  • juvenile onset diabetes (mellitus)
  • ketosis-prone diabetes (mellitus)
E10.21code
Inclusion terms
  • Type 1 diabetes mellitus with intercapillary glomerulosclerosis
  • Type 1 diabetes mellitus with intracapillary glomerulonephrosis
  • Type 1 diabetes mellitus with Kimmelstiel-Wilson disease
E00-E89chapter
Notes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.E05.8E07.0E16-E31E34.-
Index entries leading here 5
  • Diabetes, diabetic (mellitus) (sugar) E11.9
    • type 1 E10.9
      • with
        • glomerulonephrosis, intracapillary E10.21
        • glomerulosclerosis, intercapillary E10.21
        • Kimmelstiel-Wilson disease E10.21
        • nephropathy E10.21
  • Nephrosis, nephrotic (Epstein's) (syndrome) (congenital) N04.9
    • in
      • diabetes mellitus — see E08-E13 with .21
    • diabetic — see E08-E13 with .21
  • Nephritis, nephritic (albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic) N05.9
    • due to
      • diabetes mellitus — see E08-E13 with .21
  • Nephropathy N28.9
    • diabetic — see E08-E13 with .21
  • Disease, diseased — see also Syndrome
    • Kimmelstiel (-Wilson) (intercapillary polycystic (congenital) glomerulosclerosis) — see E08-E13 with .21
Alongside this code 2 same parent — E10.2
Medications 3

MED-RT files conditions by MeSH, which carves the world differently from ICD-10. These are name matches on this code's description, offered as candidates — not as an assertion that they are this code.

Additional references
AHA Coding Clinic® Licence required

Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.

Risk adjustment

CMS22HCC18 CMS28HCC37 ESRD21HCC141 · HCC18 ESRD24HCC18 RX08HCC30

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This code

Billable
yes
Code set
FY2026
Parent
E10.2
Block
E08-E13
Siblings
2

Present FY2024–FY2027.