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D68.61

Antiphospholipid syndrome

Billable FY2026 2025-10-01 → 2026-09-30
Exclusions 18 never code together
D68code
Excludes1
  • abnormal coagulation profile NOS (R79.1)R79.1
Excludes2
  • coagulation defects complicating abortion or ectopic or molar pregnancy (O00-O07, O08.1)O00-O07O08.1
  • coagulation defects complicating pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3)O45.0O46.0O67.0O72.3
D68.61code
Excludes1
  • anti-phospholipid antibody, finding without diagnosis (R76.0)R76.0
Excludes2
  • anti-phospholipid antibody with hemorrhagic disorder (D68.312)D68.312
  • lupus anticoagulant syndrome (D68.62)D68.62
D68.6code
Excludes1
  • diffuse or disseminated intravascular coagulation [DIC] (D65)D65
  • heparin induced thrombocytopenia (HIT) (D75.82-)D75.82-
  • hyperhomocysteinemia (E72.11)E72.11
D50-D89chapter
Excludes2
  • autoimmune disease (systemic) NOS (M35.9)M35.9
  • certain conditions originating in the perinatal period (P00-P96)P00-P96
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)O00-O9A
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)Q00-Q99
  • endocrine, nutritional and metabolic diseases (E00-E88)E00-E88
  • human immunodeficiency virus [HIV] disease (B20)B20
  • injury, poisoning and certain other consequences of external causes (S00-T88)S00-T88
  • neoplasms (C00-D49)C00-D49
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)R00-R94

Excludes1 — never code together. The excluded condition and this one are mutually exclusive.

Excludes2 — not included here, but the patient may have both. Code both when documented.

Instructional notes 3
D68.61code
Inclusion terms
  • Anticardiolipin syndrome
  • Antiphospholipid antibody syndrome
D68.6code
Inclusion terms
  • Other hypercoagulable states
Index entries leading here 4
  • Antiphospholipid
  • Antibody
    • antiphosphatidylglycerol R76.0
      • with
        • hypercoagulable state D68.61
    • antiphosphatidylinositol R76.0
      • with
        • hypercoagulable state D68.61
    • antiphosphatidylserine R76.0
      • with
        • hypercoagulable state D68.61
    • antiphospholipid R76.0
      • with
        • hypercoagulable state D68.61
    • anticardiolipin R76.0
      • with
        • hypercoagulable state D68.61
  • Syndrome — see also Disease
    • anticardiolipin (-antibody) D68.61
    • antiphospholipid (-antibody) D68.61
  • Anticardiolipin syndrome D68.61
Alongside this code 2 same parent — D68.6
Additional references
AHA Coding Clinic® Licence required

Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.

Risk adjustment

CMS22HCC48 ESRD21HCC48 ESRD24HCC48

Presence is a property of the code. Untick a model to hide it everywhere.

This code

Billable
yes
Code set
FY2026
Parent
D68.6
Block
D65-D69
Siblings
2

Present FY2024–FY2027.