D57.81

Other sickle-cell disorders with crisis

Not billable — category only FY2026 2025-10-01 → 2026-09-30

Exclusions 10 never code together

D57code

Excludes1

Excludes2

autoimmune disease (systemic) NOS (M35.9)M35.9
certain conditions originating in the perinatal period (P00-P96)P00-P96
complications of pregnancy, childbirth and the puerperium (O00-O9A)O00-O9A
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)Q00-Q99
endocrine, nutritional and metabolic diseases (E00-E88)E00-E88
human immunodeficiency virus [HIV] disease (B20)B20
injury, poisoning and certain other consequences of external causes (S00-T88)S00-T88
neoplasms (C00-D49)C00-D49
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)R00-R94

Excludes1 — never code together. The excluded condition and this one are mutually exclusive.

Excludes2 — not included here, but the patient may have both. Code both when documented.

Instructional notes 3

D57code

Use additional code

Inclusion terms

Official Guidelines 1 names this code

ICD-10-CM Official Guidelines for Coding and Reporting, quoted in full. Published by CMS and NCHS; in the public domain.

I.C.3 Chapter 3: Disease of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) names this code p.39

Reserved for future guideline expansion

Index entries leading here 5

Arthropathy M12.9
- gouty — see also Gout
  - in (due to)
    - sickle-cell disorders D57
Disease, diseased — see also Syndrome
- hemoglobin or Hb
  - SD D57.8
  - SE D57.8
- sickle-cell D57.1
  - elliptocytosis D57.8
Disorder (of) — see also Disease
- sickle-cell (sickling) (homozygous) — see Disease, sickle-cell
  - specified type NEC D57.8
Elliptocytosis (congenital) (hereditary) D58.1
- sickle-cell (disease) D57.8
Spherocytosis (congenital) (familial) (hereditary) D58.0
- sickle-cell (disease) D57.8

Alongside this code 1 same parent — D57.8

Subordinate codes 6

Additional references

AHA Coding Clinic® Licence required

Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.

Maps to no condition category in any loaded model.

Presence is a property of the code. Untick a model to hide it everywhere.

Present FY2024–FY2027.