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D46.C

Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality

Billable FY2026 2025-10-01 → 2026-09-30
Exclusions 2 never code together
D46code
Excludes2
  • drug-induced aplastic anemia (D61.1)D61.1
D37-D48block
Excludes1
  • neoplasms of unspecified behavior (D49.-)D49.-

Excludes1 — never code together. The excluded condition and this one are mutually exclusive.

Excludes2 — not included here, but the patient may have both. Code both when documented.

Instructional notes 12
D46.Ccode
Inclusion terms
  • Myelodysplastic syndrome with 5q deletion
  • 5q minus syndrome NOS
D46code
Use additional code
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)T36-T50
D37-D48block
Notes
  • Categories D37-D44, and D48 classify by site neoplasms of uncertain behavior, i.e., histologic confirmation whether the neoplasm is malignant or benign cannot be made.D37-D44D48
C00-D49chapter
Notes
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).C25.9
Index entries leading here 2
  • Myelodysplastic syndrome D46.9
    • with
      • 5q deletion D46.C
      • isolated del (5q) chromosomal abnormality D46.C
  • Syndrome — see also Disease
    • myelodysplastic D46.9
      • with
        • 5q deletion D46.C
        • isolated del (5q) chromosomal abnormality D46.C
    • 5q minus NOS D46.C
Alongside this code 8 same parent — D46
Additional references
AHA Coding Clinic® Licence required

Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.

Risk adjustment

CMS22HCC46 CMS28HCC19 ESRD21HCC46 ESRD24HCC46 RX08HCC16

Presence is a property of the code. Untick a model to hide it everywhere.

This code

Billable
yes
Code set
FY2026
Parent
D46
Block
D37-D48
Siblings
8

Present FY2024–FY2027.