C49.8
Malignant neoplasm of overlapping sites of connective and soft tissue
Billable FY2026 2025-10-01 → 2026-09-30
Exclusions 12 never code together
C49code
Excludes1
Excludes2
- Kaposi's sarcoma of soft tissue (C46.1)C46.1
- malignant neoplasm of heart (C38.0)C38.0
- malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)C47.-
- malignant neoplasm of peritoneum (C48.2)C48.2
- malignant neoplasm of retroperitoneum (C48.0)C48.0
- malignant neoplasm of uterine ligament (C57.3)C57.3
- mesothelioma (C45.-)C45.-
Excludes1 — never code together. The excluded condition and this one are mutually exclusive.
Excludes2 — not included here, but the patient may have both. Code both when documented.
Instructional notes 19
C49code
Includes
- malignant neoplasm of blood vessel
- malignant neoplasm of bursa
- malignant neoplasm of cartilage
- malignant neoplasm of fascia
- malignant neoplasm of fat
- malignant neoplasm of ligament, except uterine
- malignant neoplasm of lymphatic vessel
- malignant neoplasm of muscle
- malignant neoplasm of synovia
- malignant neoplasm of tendon (sheath)
C49.8code
Inclusion terms
- Primary malignant neoplasm of two or more contiguous sites of connective and soft tissue
C00-D49chapter
Notes
- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).C25.9
Index entries leading here filed at null
No alphabetic index entry points at this code.
Alongside this code 9 same parent — C49
C49.0 Malig neoplm of conn and soft tissue of head, face and neck C49.1 Malig neoplm of conn and soft tiss of upper limb, inc shldr category C49.2 Malig neoplm of conn and soft tissue of lower limb, inc hip category C49.3 Malignant neoplasm of connective and soft tissue of thorax C49.4 Malignant neoplasm of connective and soft tissue of abdomen C49.5 Malignant neoplasm of connective and soft tissue of pelvis C49.6 Malignant neoplasm of conn and soft tissue of trunk, unsp C49.9 Malignant neoplasm of connective and soft tissue, unsp C49.A Gastrointestinal stromal tumor category
Medications 2
MED-RT files conditions by MeSH, which carves the world differently from ICD-10. These are name matches on this code's description, offered as candidates — not as an assertion that they are this code.
Additional references
AHA Coding Clinic® Licence required
Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.