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A81.2

Progressive multifocal leukoencephalopathy

Billable FY2026 2025-10-01 → 2026-09-30
Exclusions 8 never code together
A80-A89block
Excludes1
  • postpolio syndrome (G14)G14
  • sequelae of poliomyelitis (B91)B91
  • sequelae of viral encephalitis (B94.1)B94.1
A00-B99chapter
Excludes1
  • certain localized infections - see body system-related chapters
Excludes2
  • carrier or suspected carrier of infectious disease (Z22.-)Z22.-
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)O98.-
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)P35-P39
  • influenza and other acute respiratory infections (J00-J22)J00-J22

Excludes1 — never code together. The excluded condition and this one are mutually exclusive.

Excludes2 — not included here, but the patient may have both. Code both when documented.

Instructional notes 11
A81code
Includes
  • diseases of the central nervous system caused by prions
Use additional code
A81.2code
Inclusion terms
  • Multifocal leukoencephalopathy NOS
A00-B99chapter
Includes
  • diseases generally recognized as communicable or transmissible
Use additional code
  • code to identify resistance to antimicrobial drugs (Z16.-)Z16.-
Index entries leading here 1
  • Leukoencephalopathy G93.49
    • multifocal (progressive) A81.2
    • progressive multifocal A81.2
Alongside this code 4 same parent — A81
Medications 1

MED-RT files conditions by MeSH, which carves the world differently from ICD-10. These are name matches on this code's description, offered as candidates — not as an assertion that they are this code.

Additional references
AHA Coding Clinic® Licence required

Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.

Risk adjustment

CMS28HCC127 ESRD21HCC52 ESRD24HCC52 RX08HCC112

Presence is a property of the code. Untick a model to hide it everywhere.

This code

Billable
yes
Code set
FY2026
Parent
A81
Block
A80-A89
Siblings
4

Present FY2024–FY2027.