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D84.81

Immunodeficiency due to conditions classified elsewhere

Billable FY2026 2025-10-01 → 2026-09-30
Exclusions 14 never code together
D84.81code
Excludes1
  • certain disorders involving the immune mechanism (D80-D83, D84.0, D84.1, D84.9)D80-D83D84.0D84.1D84.9
  • human immunodeficiency virus [HIV] disease (B20)B20
D80-D89block
Excludes1
  • autoimmune disease (systemic) NOS (M35.9)M35.9
  • functional disorders of polymorphonuclear neutrophils (D71-)D71-
  • human immunodeficiency virus [HIV] disease (B20)B20
D50-D89chapter
Excludes2
  • autoimmune disease (systemic) NOS (M35.9)M35.9
  • certain conditions originating in the perinatal period (P00-P96)P00-P96
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)O00-O9A
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)Q00-Q99
  • endocrine, nutritional and metabolic diseases (E00-E88)E00-E88
  • human immunodeficiency virus [HIV] disease (B20)B20
  • injury, poisoning and certain other consequences of external causes (S00-T88)S00-T88
  • neoplasms (C00-D49)C00-D49
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)R00-R94

Excludes1 — never code together. The excluded condition and this one are mutually exclusive.

Excludes2 — not included here, but the patient may have both. Code both when documented.

Instructional notes 7
D84.81code
Code first
  • underlying condition, such as:
  • chromosomal abnormalities (Q90-Q99)Q90-Q99
  • diabetes mellitus (E08-E13)E08-E13
  • malignant neoplasms (C00-C96)C00-C96
D80-D89block
Includes
  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis
Index entries leading here 1
  • Immunodeficiency D84.9
    • due to
      • conditions classified elsewhere D84.81
Alongside this code 2 same parent — D84.8
Additional references
AHA Coding Clinic® Licence required

Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.

Risk adjustment

CMS22HCC47 ESRD21HCC47 ESRD24HCC47 RX08HCC99

Presence is a property of the code. Untick a model to hide it everywhere.

This code

Billable
yes
Code set
FY2026
Parent
D84.8
Block
D80-D89
Siblings
2

Present FY2024–FY2027.