Reserved for future guideline expansion
D80
Immunodeficiency with predominantly antibody defects
Not billable — category only FY2026 2025-10-01 → 2026-09-30
Exclusions 12 never code together
D80-D89block
D50-D89chapter
Excludes2
- autoimmune disease (systemic) NOS (M35.9)M35.9
- certain conditions originating in the perinatal period (P00-P96)P00-P96
- complications of pregnancy, childbirth and the puerperium (O00-O9A)O00-O9A
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)Q00-Q99
- endocrine, nutritional and metabolic diseases (E00-E88)E00-E88
- human immunodeficiency virus [HIV] disease (B20)B20
- injury, poisoning and certain other consequences of external causes (S00-T88)S00-T88
- neoplasms (C00-D49)C00-D49
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)R00-R94
Excludes1 — never code together. The excluded condition and this one are mutually exclusive.
Excludes2 — not included here, but the patient may have both. Code both when documented.
Instructional notes 3
D80-D89block
Includes
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Official Guidelines 1 names this code
ICD-10-CM Official Guidelines for Coding and Reporting, quoted in full. Published by CMS and NCHS; in the public domain.
Index entries leading here filed at null
No alphabetic index entry points at this code.
Subordinate codes 10
D80.0 Hereditary hypogammaglobulinemia D80.1 Nonfamilial hypogammaglobulinemia D80.2 Selective deficiency of immunoglobulin A [IgA] D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses D80.4 Selective deficiency of immunoglobulin M [IgM] D80.5 Immunodeficiency with increased immunoglobulin M [IgM] D80.6 Antibody defic w near-norm immunoglob or w hyperimmunoglob D80.7 Transient hypogammaglobulinemia of infancy D80.8 Other immunodeficiencies with predominantly antibody defects D80.9 Immunodeficiency with predominantly antibody defects, unsp
Additional references
AHA Coding Clinic® Licence required
Official coding advice for this code. Published by the American Hospital Association. Not included in this installation.